810255P
Avanti
TopFluor™ Cholesterol
Avanti Research™ - A Croda Brand
Synonym(s):
Bodipy Cholesterol; Bdp-Chol
Sign Into View Organizational & Contract Pricing
All Photos(2)
About This Item
Empirical Formula (Hill Notation):
C36H51BF2N2O
CAS Number:
Molecular Weight:
576.61
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.25
Recommended Products
description
23-(dipyrrometheneboron difluoride)-24-norcholesterol
Assay
>99% (TLC)
form
powder
packaging
pkg of 1 × 1 mg (810255P-1mg)
pkg of 1 × 10 mg (810255P-10mg)
pkg of 1 × 5 mg (810255P-5mg)
manufacturer/tradename
Avanti Research™ - A Croda Brand
shipped in
dry ice
storage temp.
−20°C
General description
Biomolecules attached to BODIPY, is readily absorbed in the visible light. It results in greater fluorescence quantum yields. It is highly photostable and less sensitive to change in polarity and pH.
Application
TOPFLUOR™Cholesterol is suitable:
- for cholesterol-uptake assay
- for BODIPY cholesterol labeling in live cell experiments
- for the formation of giant Janus liposomes via poly(vinyl alcohol) (PVA)-assisted lipid swelling
Biochem/physiol Actions
BODIPY labelled cholesterol has similar properties to that of the naïve cholesterol. This serves as a cholesterol marker for live cells and aids in trafficking intracellular cholesterol. It might also help in indicating lipid storage diseases.
Packaging
5 mL Amber Glass Screw Cap Vial (810255P-10mg)
5 mL Amber Glass Screw Cap Vial (810255P-1mg)
5 mL Amber Glass Screw Cap Vial (810255P-5mg)
Legal Information
Avanti Research is a trademark of Avanti Polar Lipids, LLC
TopFluor is a trademark of Avanti Polar Lipids, LLC
also commonly purchased with this product
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Sorry, we don't have COAs for this product available online at this time.
If you need assistance, please contact Customer Support.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
James E Shaw et al.
Biophysical journal, 90(6), 2170-2178 (2005-12-20)
Coupling atomic force microscopy (AFM) with high-resolution fluorescence microscopy is an attractive means of identifying membrane domains by both physical topography and fluorescence. We have used this approach to study the ability of a suite of fluorescent molecules to probe
Functional inhibition of acid sphingomyelinase disrupts infection by intracellular bacterial pathogens
Cockburn CL, et al.
Life science alliance, 2(2), e201800292-e201800292 (2019)
Salvatore Chiantia et al.
Biochimica et biophysica acta, 1778(5), 1356-1364 (2008-03-19)
Ceramide-induced alterations in the lateral organization of membrane proteins can be involved in several biological contexts, ranging from apoptosis to viral infections. In order to investigate such alterations in a simple model, we used a combined approach of atomic force
Robert M Littleton et al.
BMC complementary and alternative medicine, 12, 105-105 (2012-07-25)
Consumers are increasingly turning to plant-based complementary and alternative medicines to treat hypercholesterolemia. Many of these treatments are untested and their efficacy is unknown. This multitude of potential remedies necessitates a model system amenable to testing large numbers of organisms
Impaired Cholesterol-Uptake Capacity of HDL Might Promote Target-Lesion Revascularization by Inducing Neoatherosclerosis After Stent Implantation
Nagano Y, et al.
Journal of the American Heart Association, 8(9), e011975-e011975 (2019)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service