M13807
4-Methoxycinnamic acid, predominantly trans
99%
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About This Item
Linear Formula:
CH3OC6H4CH=CHCO2H
CAS Number:
Molecular Weight:
178.18
EC Number:
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.23
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Quality Level
Assay
99%
form
liquid crystal
mp
170-173 °C (lit.)
transition temp
crystalline phase to nematic phase 173.5 °C
nematic phase to isotropic phase 190 °C
SMILES string
COc1ccc(\C=C\C(O)=O)cc1
InChI
1S/C10H10O3/c1-13-9-5-2-8(3-6-9)4-7-10(11)12/h2-7H,1H3,(H,11,12)/b7-4+
InChI key
AFDXODALSZRGIH-QPJJXVBHSA-N
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Natasha Cook et al.
The Australasian journal of dermatology, 43(2), 133-135 (2002-05-02)
We report a case of photoallergic contact dermatitis to two sunscreen agents, methoxycinnamate and oxybenzone, occurring in a 6-year-old Asian boy.
H V Meyers et al.
Carbohydrate research, 197, 15-32 (1990-03-25)
This study completes the spectroscopic basis for a novel oligosaccharide microanalytical method, wherein a derivatization sequence provides monosaccharide subunits bearing two types of exciton-coupling chromophore groups ("bichromophoric") for circular dichroic spectroscopy, namely 4-bromobenzoate (lambda max 245 nm) and 4-methoxycinnamate (lambda
Sirintorn Yibchok-anun et al.
Basic & clinical pharmacology & toxicology, 102(5), 476-482 (2008-03-19)
This study investigated the effect of p-methoxycinnamic acid (p-MCA) on plasma glucose and insulin concentrations in normal and streptozotocin-induced diabetic rats. In both fasting and glucose-loading conditions, an oral administration of p-MCA (40-100 mg/kg) significantly decreased plasma glucose and also
S Adisakwattana et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 43(11), 766-773 (2011-10-20)
p-Methoxycinnamic acid (p-MCA) is a cinnamic acid derivative that shows various pharmacologic actions such as hepatoprotective and antihyperglycemic activities. The present study was to elucidate the mechanisms by which p-MCA increases [Ca²⁺]i and insulin secretion in INS-1 cells. p-MCA (100
So Ra Kim et al.
British journal of pharmacology, 135(5), 1281-1291 (2002-03-06)
1. We previously reported that four new phenylpropanoid glycosides and six known cinnamate derivatives isolated from roots of Scrophularia buergeriana Miquel (Scrophulariaceae) protected cultured cortical neurons from neurotoxicity induced by glutamate. Here, we have investigated the structure-activity relationships in the
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