I2633

Cardiogreen

Powder

• Synonym(s): Foxgreen, IC Green, Indocyanine green
• Empirical Formula (Hill Notation): C₄₃H₄₇N₂NaO₆S₂
• CAS Number: 3599-32-4
• Molecular Weight: 774.96
• Beilstein: 4115884
• EC Number: 222-751-5
• MDL number: MFCD00013078
• UNSPSC Code: 12171500
• PubChem Substance ID: 24895979
• NACRES: NA.47

Properties

• Product Name: Cardiogreen, polymethine dye
• form: powder
• composition: Dye content, ≥75%
• technique(s): titration: suitable
• color: green to very dark green
• solubility: water: 0.01 g/mL
• application(s): diagnostic assay manufacturing; hematology; histology
• storage temp.: room temp
• SMILES string: [Na+].CC1(C)/C(=C\C=C\C=C\C=C\C2=[N+](CCCCS([O-])(=O)=O)c3ccc4ccccc4c3C2(C)C)N(CCCCS([O-])(=O)=O)c5ccc6ccccc6c15
• InChI: 1S/C43H48N2O6S2.Na/c1-42(2)38(44(28-14-16-30-52(46,47)48)36-26-24-32-18-10-12-20-34(32)40(36)42)22-8-6-5-7-9-23-39-43(3,4)41-35-21-13-11-19-33(35)25-27-37(41)45(39)29-15-17-31-53(49,50)51;/h5-13,18-27H,14-17,28-31H2,1-4H3,(H-,46,47,48,49,50,51);/q;+1/p-1
• InChI key: MOFVSTNWEDAEEK-UHFFFAOYSA-M

Description

General description

Cardiogreen is a negatively charged polymethine dye that forms noncovalent fluorescent complexes with proteins. This "pseudofluorogenic" property has been utilized for protein determination by capillary electrophoresis with diode laser-induced fluorescence detection.

Application

Cardiogreen has been used to resolve several labeled proteins including: human serum albumin, ribonuclease A, transferrin, and cytochrome c.
Cardiogreen has been used as an intraocular capsular stain. It has been used in the dye-dilution method for cardiac output.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Analysis Note

solubility: 0.01g in 10mL H₂O : green to very dark green

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H315,H319,H335
• Precautionary Statements: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves