Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor used for regulating plant growth and development. The working concentration of the product would have to be determined by the end user, and the minimum purity specification is 97.5%. The compound is soluble in DMSO at 5mg/mL. For more information on the topic, it may be helpful to review the relevant publications.
SML1406
Brassinazole
≥98% (HPLC), powder, brassinosteroid biosynthesis inhibitor
Synonym(s):
β-[(4-chlorophenyl)methyl]-α-methyl-α-phenyl-1H-1,2,4-triazole-1-ethanol, (αR,βS)-rel-β-[(4-chlorophenyl)methyl]-α-methyl-α-phenyl-1H-1,2,4-triazole-1-ethanol
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About This Item
Empirical Formula (Hill Notation):
C18H18ClN3O
CAS Number:
Molecular Weight:
327.81
UNSPSC Code:
51111800
PubChem Substance ID:
NACRES:
NA.77
Pricing and availability is not currently available.
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Product Name
Brassinazole, ≥98% (HPLC)
Quality Level
Assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 5 mg/mL, clear (warmed)
storage temp.
2-8°C
SMILES string
ClC1=CC=C(C[C@@H](N2N=CN=C2)[C@@](C)(O)C3=CC=CC=C3)C=C1
InChI
1S/C18H18ClN3O/c1-18(23,15-5-3-2-4-6-15)17(22-13-20-12-21-22)11-14-7-9-16(19)10-8-14/h2-10,12-13,17,23H,11H2,1H3/t17-,18+/m1/s1
InChI key
YULDTPKHZNKFEY-MSOLQXFVSA-N
Application
Brassinazole has been used in phenotype analyses to detect morphological changes in G-protein β subunit agb1 mutants.[1]
Biochem/physiol Actions
Brassinazole induces dwarfism and morphological changes in Arabidopsis, which results in similarity with brassinosteroid deficient mutants. These changes were neutralized by brassinolide treatment, indicating that brassinazole leads to brassinolide deficiency in Arabidopsis.[2]
Brassinazole is an inhibitor of the biosynthesis of brassinosteroids, steroid hormones essential for plant growth and development.
Brassinazole is an inhibitor of the biosynthesis of brassinosteroids, steroid hormones essential for plant growth and development. It has been used to study brassinosteroids function.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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T Asami et al.
Plant physiology, 123(1), 93-100 (2000-05-12)
Screening for brassinosteroid (BR) biosynthesis inhibitors was performed to find chemicals that induce dwarfism in Arabidopsis, mutants that resembled BR biosynthesis mutants that can be rescued by BR. Through this screening experiment, the compound brassinazole was selected as the most
Lijiang Hou et al.
Plant & cell physiology, 60(8), 1761-1777 (2019-05-18)
Brassinosteroid (BR) plays an important role in plant development and biotic and abiotic stress tolerance, but its specific function remains largely unknown in wheat (Triticum aestivum L.), preventing its utilization in this important crop. In this study, the function of
Zhongtao Jia et al.
Plant physiology, 183(3), 998-1010 (2020-05-14)
Root developmental plasticity enables plants to adapt to limiting or fluctuating nutrient conditions in the soil. When grown under nitrogen (N) deficiency, plants develop a more exploratory root system by increasing primary and lateral root length. However, mechanisms underlying this
Arabidopsis G-Protein β Subunit AGB1 Interacts with BES1 to Regulate Brassinosteroid Signaling and Cell Elongation.
Zhang T, et al.
Frontiers in Plant Science, 8, 2225-2225 (2018)
Xuejiao Cheng et al.
The Plant cell, 32(4), 923-934 (2020-02-16)
Six subspecies of hexaploid wheat (Triticumaestivum) have been identified, but the origin of Indian dwarf wheat (Triticum sphaerococcum), the only subspecies with round grains, is currently unknown. Here, we isolated the grain-shape gene Tasg-D1 in Tsphaerococcum via positional cloning. Tasg-D1
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What is the function, applicable concentration, and preparation method for this product?
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What is the function, applicable concentration, and preparation method for this product?
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Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor. Brassinazole is used for regulating plant growth and development. It may be helpful to review the following publications below to obtain more information on the topic: https://www.sigmaaldrich.com/search/sml1406focus=papers&page=1&perpage=30&sort=relevance&term=sml1406&type=citation_search The working concentration of the product would have to be determined by the end user. The minimum purity specification is 97.5%. The compound is soluble in DMSO at 5mg/mL.
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