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W530066

Sigma-Aldrich

Tocopherols

mixed, Low-α type, FCC, FG

Synonym(s):

Methyltocols

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About This Item

CAS Number:
1406-66-2
UNSPSC Code:
12164502
eCl@ss:
34058016
NACRES:
NA.21
Organoleptic:
faint
grade:
FG
Kosher
biological source:
vegetable oil
food allergen:
soybeans

biological source

vegetable oil

Quality Level

400

grade

FG
Kosher

reg. compliance

EU Regulation 1333/2008 & 178/2002
FCC
FDA 21 CFR 117
FDA 21 CFR 184.1890

refractive index

n20/D 1.501

bp

>200 °C

density

0.930 g/mL at 25 °C

application(s)

flavors and fragrances

Documentation

see Safety & Documentation for available documents

food allergen

soybeans

Organoleptic

faint

SMILES string

O1C(CCc2c1c(c(c(c2)O)C)C)(CCCC(CCCC(CCCC(C)C)C)C)C

InChI

1S/C28H48O2/c1-20(2)11-8-12-21(3)13-9-14-22(4)15-10-17-28(7)18-16-25-19-26(29)23(5)24(6)27(25)30-28/h19-22,29H,8-18H2,1-7H3

InChI key

QUEDXNHFTDJVIY-UHFFFAOYSA-N

General description

Tocopherols (mixture of D-α, D-β, D-Δ, and D-γ-tocopherols) are the isomers of Vitamin E.

Application

Antioxidant used with fats and oils to delay rancidity onset

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

>392.0 °F - closed cup

Flash Point(C)

> 200 °C - closed cup

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Certificates of Analysis (COA)

Lot/Batch Number
SHBQ0117
SHBN3969
SHBM8140
MKCJ3479
MKCB7546

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Jihyeung Ju et al.
Carcinogenesis, 31(4), 533-542 (2009-09-15)
The cancer-preventive activity of vitamin E has been studied. Whereas some epidemiological studies have suggested a protective effect of vitamin E against cancer formation, many large-scale intervention studies with alpha-tocopherol (usually large doses) have not demonstrated a cancer-preventive effect. Studies
Jonathan Himmelfarb et al.
Journal of the American Society of Nephrology : JASN, 25(3), 623-633 (2013-12-29)
Increased markers of oxidative stress and acute-phase inflammation are prevalent in patients undergoing maintenance hemodialysis therapy (MHD), and are associated with increased mortality and hospitalization rates and decreased erythropoietin responsiveness. No adequately powered studies have examined the efficacy of antioxidant
Ingrid Elisia et al.
American journal of physiology. Gastrointestinal and liver physiology, 305(12), G940-G949 (2013-10-19)
The present study investigates the relative ability of α-, γ-, and δ-tocopherol (Toc) to modulate cell signaling events that are associated with inflammatory responses in fetal-derived intestinal (FHs 74 Int) cells. Secretion of the proinflammatory cytokine IL-8 in FHs 74
New insights into the function of tocopherols in plants.
Sergi Munné-Bosch et al.
Planta, 218(3), 323-326 (2003-10-31)
Dean DellaPenna et al.
Annual review of plant biology, 57, 711-738 (2006-05-04)
Carotenoids and tocopherols are the two most abundant groups of lipid-soluble antioxidants in chloroplasts. In addition to their many functional roles in photosynthetic organisms, these compounds are also essential components of animal diets, including humans. During the past decade, a
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