Ethanol is commonly used as a solvent for reconstitution of this product for cell culture applications. Although solubility in ethanol is not a tested specification for batch release, this product is known to dissolve in ethanol up to a concentration of 20 mg/mL. Sonication is not necessary for reconstitution in ethanol.
O1383
Oleic acid
BioReagent, suitable for cell culture
Synonym(s):
cis-9-Octadecenoic acid, Elainic acid
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All Photos(2)
About This Item
Linear Formula:
CH3(CH2)7CH=CH(CH2)7COOH
CAS Number:
Molecular Weight:
282.46
Beilstein:
1726542
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:
NACRES:
NA.75
Pricing and availability is not currently available.
Recommended Products
biological source
palm oil
vapor pressure
1 mmHg ( 176 °C)
product line
BioReagent
Assay
≥99% (GC)
form
viscous liquid
technique(s)
cell culture | mammalian: suitable
refractive index
n20/D 1.459 (lit.)
bp
194-195 °C/1.2 mmHg (lit.)
mp
13-14 °C (lit.)
solubility
ethanol: soluble
density
0.89 g/mL at 25 °C (lit.)
0.89 g/mL at 25 °C (lit.)
storage temp.
−20°C
SMILES string
CCCCCCCC\C=C/CCCCCCCC(O)=O
InChI
1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
InChI key
ZQPPMHVWECSIRJ-KTKRTIGZSA-N
Gene Information
human ... SOAT1(6646) , SOAT2(8435)
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General description
Oleic acid is a mono-unsaturated omega-9 fatty acid created by dehydrogenation of stearic acid. It is then further dehydrogenated and elongated to create members of the n-9 family of fatty acids. Oleic acid is not an essential fatty acid (EFA); however, providing it to cells in culture reduces energy demand.
Oleic acid mediates complete oxidation of fatty acid in sirtuin1- proliferator-activated receptor γ coactivator−1α (SIRT1-PGC-1α) signalling pathway. Oleic acid shows anti-inflammatory properties related to atherosclerosis and insulin resistant state.[1] Oleic acid inhibits permeability in gap junctions and promotes glucose uptake in astrocytes. Oleic acid aids in neural cell proliferation by increasing glucose uptake and by protein kinase C (PKC) activation. Oleic acid is essential for axonal growth and neuronal clustering.[2]
Application
Packaging
Sealed ampule.
Caution
Unsaturated fatty acids are subject to oxidation and peroxidation. Consider complexed fatty acid supplements.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Certificates of Analysis (COA)
Lot/Batch Number
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Hello. I would like to know if it is necessary to sonicate the oleic acid before stimulation? what is the best solvent? Thank you!
1 answer-
Helpful?
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What is the concentration of this oleic acid and what solvent do I need to make dilution
1 answer-
This product is a neat or pure liquid and has not been diluted. This material has a density of 0.890 g/mL and a molecular weight of 282.46 g/mol. The minimum purity is 99%, thus the molarity will vary slightly from lot to lot. The molarity can range from 3.12 M (99%) to 3.15 M (100%).
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What is the concentration of this product-O1383-25G?
1 answer-
The concentration of this product can be determined using the lot-specific purity reported in the Certificate of Analysis, as well as the density and compound molecular weight. This product has a density of 0.89 g/mL and a molecular weight of 282.46 g/mol. The minimum purity is 99%, thus the molarity will vary slightly from lot to lot. The molarity can range from 3.12 M (99%) to 3.15 M (100%).
Helpful?
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Has product O1383-25g been received in a glass container or ampule?
1 answer-
Based on the packaging information, product O1383-25g has been received in a glass ampule.
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