The positive control is glucose 6 phosphate dehydrogenase from Leuconostoc mesenteroides, purified from E. coli.
MAK015
Glucose-6-Phosphate Dehydrogenase Activity Assay Kit
sufficient for 100 colorimetric tests
Synonym(s):
G-6-PD Activity Assay Kit
Sign Into View Organizational & Contract Pricing
All Photos(3)
About This Item
UNSPSC Code:
12161503
NACRES:
NA.84
Pricing and availability is not currently available.
Recommended Products
usage
sufficient for 100 colorimetric tests
detection method
colorimetric
relevant disease(s)
cancer; hematological disorder
storage temp.
−20°C
Gene Information
human ... H6PD(9563)
mouse ... H6PD(100198)
rat ... H6PD(298655)
General description
Glucose-6-phosphate dehydrogenase (G6PDH) catalyzes the conversion of glucose-6-phosphate to 6-phosphoglucono-δ-lactone, the first and rate-limiting step of the pentose phosphate pathway (PPP).[1] The PPP pathway critical for maintaining the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH) and for the production of pentose sugars.[2] The NADPH produced is critical for redox regulation via the regeneration of GSH and for providing reducing equivalents for fatty acid biosynthesis.[3] Deficiencies in G6PDH predisposes individuals to non-immune hemolytic anemia.[4]
Application
Suitability
Suitable for the measurement of Glucose-6-phosphate dehydrogenase (G6PDH) activity in various tissues and cells.
Principle
In the glucose-6-phosphate dehydrogenase assay kit, glucose-6-phosphate is oxidized to generate a product which is specifically detected by colorimetric (450 nm) assay. The G6PDH Assay Kit can detect G6PDH activity as low as 0.04mU G6PDH per well.
related product
Product No.
Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Living with Glucose-6-Phosphate Dehydrogenase Deficiency
Devi A S, et al.
Journal of nursing science and practice., 6(1) (2016)
Redox Regulation of Cell Survival.
Dunyaporn T, et al.
Antioxidants & Redox Signaling, 10(8), 1343-1374 (2008)
Rapid Elevation in CMPF May Act As a Tipping Point in Diabetes Development
Ying L, et al.
Cell Reports, 14(12), 2889-2900 (2016)
Nuclear Heme Oxygenase-1 (HO-1) Modulates Subcellular Distribution and Activation of Nrf2, Impacting Metabolic and Anti-oxidant Defenses.
Chhanda B, et al.
The Journal of Biological Chemistry, jbc-M114 (2014)
Signaling Transduction and Metabolomics
Ronald H, et al.
Hematology (2018)
-
Is the positive control an enzyme for dehydrogenase?
1 answer-
Helpful?
-
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
