31404
Dextran sulfate sodium salt from Leuconostoc spp.
Mr 5,000
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About This Item
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biological source
(Leuconostoc spp.)
form
powder
mol wt
Mr 5,000
composition
Sulfur Content, 16.0-20.0%
loss
≤10% loss on drying
useful pH range
6.0-8.0 (10 g/L)
solubility
H2O: 0.1 g/mL, clear, colorless to slightly yellow
water: 100 g/L at 25 °C (77 °F )
H2O: freely soluble 50 mg/mL, clear
storage temp.
room temp
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Application
Dextran sulfate sodium salt from Leuconostoc sp. is a polyanion used as a test reagent for testing its capability to rupture the extracellular enveloped virus (EEV) outer membrane. It has also been used for assessing the impact of TLR4 monoclonal antibody on the growth of dextran-sulfate-sodium-(DSS)-induced colitis.
Biochem/physiol Actions
Dextran is a mixture of glucose polymers of varying size and geometry.Dextran in the form of dextran sulphate sodium acts as an anticoagulant. Dextran interferes with blood clot formation by acting on blood coagulation factors and the function of platelets. It prolongs the time required for formation of the clot and decreases the maximum clot strength. The disturbance of homeostasis by dextran may cause increased bleeding, colitis and kidney failure.
Preparation Note
prepared from dextran with Mr ~5000
Other Notes
To gain a comprehensive understanding of our extensive range of Dextrans for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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