MAB8044
Anti-Adenovirus 1,2,5,6 Antibody, clone 7/48-7a
ascites fluid, clone 7/48-7a, Chemicon®
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About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
ascites fluid
clone
7/48-7a, monoclonal
species reactivity
human
manufacturer/tradename
Chemicon®
technique(s)
immunofluorescence: suitable
isotype
IgG1
shipped in
wet ice
General description
Adenoviruses are 65-80 nm, non-enveloped, regular icosahedron pathogens often associated with respiratory and gastrointestinal illness as well as conjunctivitis. Well over 40 types of adenoviruses have currently been recognized. In addition to their deleterious effects, adenoviruses have been used in vaccine production and in gene therapy. They also have the ability to trigger cell proliferation by interfering with host cellular anti-oncogenes. Since they are easy to prepare, multiple quickly and efficiently, and have the ability to infect and deliver their genome (including researcher-created constructs) to the nucleus of a variety of post-mitotic cells, adenoviruses are extremely valuable in research and medical applications ranging from virus/host cell interaction to the insertion of novel genes or regulatory mechanisms into eukaryotic cellular systems, to delivery of therapeutic anti-cancer genes.
Specificity
Adenovirus 1,2,5,6
Immunogen
Adenovirus 1,2,5,6 hexon protein
Application
Anti-Adenovirus 1, 2, 5, 6 Antibody, clone 7/48-7a is an antibody against Adenovirus 1 for use in IF.
IFA.
Optimal working dilutions must be determined by end user.
Optimal working dilutions must be determined by end user.
Research Category
Infectious Diseases
Infectious Diseases
Research Sub Category
Infectious Diseases - Viral
Infectious Diseases - Viral
Physical form
Ascites
Storage and Stability
Maintain at -20°C in convenient aliquots for up to 12 months. Do not store in a diluted format.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage Class Code
10 - Combustible liquids
WGK
nwg
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Infection with replication-deficient adenovirus induces changes in the dynamic instability of host cell microtubules.
Warren, JC; Rutkowski, A; Cassimeris, L
Molecular Biology of the Cell null
Rapid detection and serotyping of adenovirus by direct immunofluorescence.
Wood, S R, et al.
Journal of Medical Virology, 51, 198-201 (1997)
The contributions of microtubule stability and dynamic instability to adenovirus nuclear localization efficiency.
James C Warren,Lynne Cassimeris
Cell Motility and the Cytoskeleton null
Weidong Xu et al.
Molecular therapy : the journal of the American Society of Gene Therapy, 22(8), 1504-1517 (2014-05-06)
We are interested in developing oncolytic adenoviruses for the treatment of prostate cancer (PCa) bone metastases. A key limitation of Adenovirus 5 (Ad5) is that upon systemic administration, it produces major liver and systemic toxicities. To address this issue, a
Natalya Kaverina et al.
Autophagy, 13(11), 1905-1923 (2017-10-06)
Formation of metastases, also known as cancer dissemination, is an important stage of breast cancer (BrCa) development. KISS1 expression is associated with inhibition of metastases development. Recently we have demonstrated that BrCa metastases to the brain exhibit low levels of
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