8.53008

Boc-His(Dnp)-OH isopropanol

Novabiochem^®

• Synonym(s): Boc-His(Dnp)-OH isopropanol, N-α-t.-Boc-N-im-dinitrophenyl-L-histidine isopropanol
• Empirical Formula (Hill Notation): C₁₇H₁₉N₅O₈ · xC₃H₈O
• Molecular Weight: 421.36
• UNSPSC Code: 12352209
• NACRES: NA.22

Properties

• Quality Level: 200
• product line: Novabiochem^®
• Assay: ≥98% (TLC)
• form: powder
• reaction suitability: reaction type: Boc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• storage temp.: 15-25°C

Description

General description

Standard building block for introduction of histidine amino-acid residues by Boc SPPS. The Dnp group is stable to HF and TFMSA. Normally removed with thiophenol prior to HF treatment.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Linkage

Replaces: 04-12-0023

Analysis Note

Color (visual): white to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in EtOAc): +52.5 - +59.5 °
Purity (TLC(011C)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clear soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable