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112720

Sigma-Aldrich

N,N-Diethylethylenediamine

≥99%

Synonym(s):

2-Diethylaminoethylamine

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About This Item

Linear Formula:
(C2H5)2NCH2CH2NH2
CAS Number:
100-36-7
Molecular Weight:
116.20
Beilstein:
605299
EC Number:
202-844-7
MDL number:
MFCD00008176
UNSPSC Code:
12352100
PubChem Substance ID:
24847111
NACRES:
NA.22
Pricing and availability is not currently available.

Assay

≥99%

refractive index

n20/D 1.436 (lit.)

bp

145-147 °C (lit.)

density

0.827 g/mL at 25 °C (lit.)

functional group

amine

SMILES string

CCN(CC)CCN

InChI

1S/C6H16N2/c1-3-8(4-2)6-5-7/h3-7H2,1-2H3

InChI key

UDGSVBYJWHOHNN-UHFFFAOYSA-N

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Application

N,N-Diethylethylenediamine was used in the oxidative amidation of hydrogen phosphonate diesters in the synthesis of oligonucleotides[1].
N,N-diethylethylenediamine was used to develop melanin targeted PET and single-photon emission computed tomography (SPECT) imaging agents for melanoma[2].

Signal Word

Danger

Hazard Statements

H226,H311,H314,H332

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Flam. Liq. 3 - Skin Corr. 1A

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

89.6 °F - closed cup

Flash Point(C)

32 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
SDBB0704
STBL1831
STBK7442
STBK2601
STBK0001

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Hongguang Liu et al.
Molecular pharmaceutics, 10(9), 3384-3391 (2013-08-10)
Radiofluorinated benzamide and nicotinamide analogues are promising molecular probes for the positron emission tomography (PET) imaging of melanoma. Compounds containing aromatic (benzene or pyridine) and N,N-diethylethylenediamine groups have been successfully used for development of melanin targeted PET and single-photon emission
J M Dagle et al.
Nucleic acids research, 28(10), 2153-2157 (2000-04-25)
We have designed a new class of modified antisense oligodeoxyribonucleotides (ODN) consisting of a central contiguous stretch of 6-8 unmodified nucleotides flanked by 3'- and 5'-regions containing several nucleotides joined by cationic internucleoside linkages. The positive charge results from modification
Diana Salakhieva et al.
International journal of pharmaceutics, 517(1-2), 234-246 (2016-12-10)
A series of 14 cationic derivatives of poly(aspartic acid) i.e. cationic polyaspartamides with different (dialkylamino)alkyl and alkyl or hydroxyalkyl side groups was synthesized by nucleophilic addition on polysuccinimide. The resulting polyaspartamides have moderate amphiphilic properties. Relationships between the structure and
Vincenzo Taresco et al.
Materials science & engineering. C, Materials for biological applications, 52, 72-81 (2015-05-09)
The application of magnetic nanoparticles (MNPs) in medicine is considered much promising especially because they can be handled and directed to specific body sites by external magnetic fields. MNPs have been investigated in magnetic resonance imaging, hyperthermia and drug targeting.
Feng-Yun J Huang et al.
International journal of nanomedicine, 10, 463-473 (2015-01-28)
In this study, the (188)Re-labeled PEGylated nanoliposome ((188)Re-liposome) was prepared and evaluated as a therapeutic agent for glioma. The reporter cell line, F98(luc) was prepared via Lentivector expression kit system and used to set up the orthotopic glioma-bearing rat model
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Questions

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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