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HEPES sodium salt

ULTROL® Grade, ≥99% dry basis (titration), zwitterionic N-substituted aminosulfonic acid buffer

Synonym(s):

HEPES, Sodium Salt, ULTROL® Grade, N-2-Hydroxyethylpiperazine-Nʹ-2-ethanesulfonic Acid, Na

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About This Item

Empirical Formula (Hill Notation):
C8H17N2O4S · Na
CAS Number:
75277-39-3
Molecular Weight:
260.29
UNSPSC Code:
12161704
NACRES:
NA.25

Quality Level

100

assay

≥99% dry basis (titration)

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
desiccated (hygroscopic)

color

white

pKa (20 °C)

7.6

solubility

water: 1.0 M

anion traces

chloride (Cl-): <0.01%
sulfate (SO42-): <0.05%

cation traces

heavy metals: <1 ppm

shipped in

ambient

storage temp.

15-25°C

InChI

1S/C8H18N2O4S.Na/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;/h11H,1-8H2,(H,12,13,14);/q;+1/p-1

InChI key

RDZTWEVXRGYCFV-UHFFFAOYSA-M

General description

A zwitterionic N-substituted aminosulfonic acid buffer(Absorbance: <0.10 at 260 nm, 1.0 mM, H2O). Active in the pH range of 6.0 to 8.5. Has a pKa of 7.6 at 20°C.
A zwitterionic N-substituted aminosulfonic acid buffer. Useful in the pH 6.8-8.2 range. Has a pKa of 7.55 at 25°C.
Absorbance (1.0 mM, H2O, 260 nm):<0.10.

Application


  • 3,6-O-[N-(2-Aminoethyl)-acetamide-yl]-chitosan exerts antibacterial activity by a membrane damage mechanism.: This study explores the antibacterial mechanisms of a chitosan derivative, which could be related to the buffering capabilities of HEPES in maintaining the stability and exposure of functional groups necessary for antibacterial activity (Yan et al., 2016).

Warning

Toxicity: Standard Handling (A)

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
ULTROL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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