Skip to Content
MilliporeSigma
All Photos(4)

Documents

A0278

Sigma-Aldrich

L-Ascorbic acid

reagent grade

Synonym(s):

L-Threoascorbic acid, Antiscorbutic factor, Vitamin C

Sign Into View Organizational & Contract Pricing
All Photos(4)

About This Item

Empirical Formula (Hill Notation):
C6H8O6
CAS Number:
50-81-7
Molecular Weight:
176.12
Beilstein/REAXYS Number:
84272
EC Number:
200-066-2
MDL number:
MFCD00064328
UNSPSC Code:
12352209
PubChem Substance ID:
24890417
NACRES:
NA.26

biological source

synthetic

grade

reagent grade

assay

≥98% (with Iodine, titration)

form

powder

technique(s)

HPLC: suitable

color

white to light yellow

pH

1.0-2.5 (25 °C, 176 g/L in water)

mp

190-194 °C (dec.)

solubility

water: soluble 50 mg/mL

SMILES string

OC([C@]([C@@H](O)CO)([H])O1)=C(O)C1=O

InChI

1S/C6H8O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-10H,1H2/t2-,5+/m0/s1

InChI key

CIWBSHSKHKDKBQ-JLAZNSOCSA-N

Gene Information

human ... SLC23A2(9962)

Looking for similar products? Visit Product Comparison Guide

General description

Ascorbic Acid, also known as Vitamin C, is a six-carbon lactone produced by plants and some animal species but not by humans and other primates. It is a water-soluble vitamin.

Application

L-Ascorbic acid has been used as a standard in high performance liquid chromatography (HPLC) for quantification of L-ascorbic acid.
L-Ascorbic acid may be used as standard in assay for erythrocyte hemolysis mediated by peroxyl free radicals. It may be used for the reduction of graphene oxide sheets.

Biochem/physiol Actions

L-Ascorbic acid is an anti-oxidant. L-Ascorbic acid (vitamin C) is important for many enzymatic reactions for maintaining prosthetic metal ions in their reduced forms (for example, Fe2+, Cu+). It protects tissues from oxidative damage by scavenging free radicals. It has mild reductive ability and nontoxic property. It is commonly employed reductant in the laboratory. Colorimetric determination of ascorbic acid in plasma using acid phosphotungstate has been reported.
L-ascorbic acid modified poly(ester urethane)s might facilitate soft tissue regeneration. It also helps in increasing iron absorption by tissues. In addition, it aids in tyrosine metabolism and microsomal drug metabolism.

Caution

May darken in storage.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Synthesis and characterization of cycloaliphatic hydrophilic polyurethanes, modified with L-ascorbic acid, as materials for soft tissue regeneration
Kucinska-Lipka J, et al.
Materials Science & Engineering. C, Materials For Biological Applications, 75(3), 671-681 (2017)
Gemma Rush et al.
Parasitology, 146(9), 1184-1187 (2019-03-13)
Bovine trichomoniasis is a notifiable, reproductive disease of cattle caused by the parasite Tritrichomonas foetus. Culturing with modified Diamond's medium (MDM) is required to increase the low number of organisms received from a preputial sample, but is limited in application
Dehydrofreezing of pineapple
Ramallo LA and Mascheroni RH
Journal of Food Engineering, 99(3), 269-275 (2010)
Jk Psc Quick Review for Medical Officers: A Useful Manual For NEET, AIIMS and PGI Md/Ms. Entrance Exams (2018)
Solubilities of magnesium-l-ascorbate, calcium-l-ascorbate, magnesium-l-glutamate, magnesium-d-gluconate, calcium-d-gluconate, calcium-d-heptagluconate, l-aspartic acid, and 3-nitrobenzoic acid in water
Mishelevich A and Apelblat A
The Journal of Chemical Thermodynamics, 40(5), 897-900 (2008)
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service