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Anti-RGS17 antibody produced in rabbit

Name: Anti-RGS17 antibody produced in rabbit
Brand: SIGMA
Price: 2400 PLN

Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution

Synonym(s):

Anti-Regulator of g-protein signaling 17, Anti-Rgs-17, Anti-Rgsz2

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Pack Size	SKU	Availability	Price
100 μL		Please contact Customer Service for Availability	PLN 2,400.00

About This Item

UNSPSC Code:

12352203

NACRES:

NA.41

Human Protein Atlas Number:

HPA022276

Conjugate:

unconjugated

Clone:

polyclonal

Application:

IHC, WB

Citations:

PLN 2,400.00

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Properties

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

product line

Prestige Antibodies^® Powered by Atlas Antibodies

form

buffered aqueous glycerol solution

species reactivity

human

enhanced validation

recombinant expression
Learn more about Antibody Enhanced Validation

technique(s)

immunohistochemistry: 1:50-1:200, western blot: 0.04-0.4 μg/mL

immunogen sequence

NEGTPAVSQAPGNQRPNNTCCFCWCCCCSCSCLTVRNEERGENAGRPTHTTKMESIQVLEECQNPTAEEVLSWSQNFDKMMKAPAGRNLFREFLRTEY

UniProt accession no.

Q9UGC6

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... RGS17(26575)

Description

General description

RGS17 (Regulator of G-protein signaling 17) is majorly involved in the regulation of G protein-coupled receptor signaling pathway. Specifically, it suppresses receptor signaling via G(i/o), G(z), and G(q) over G(s), which in turn enhances cAMP-dependent signaling and inhibits calcium signaling.

Immunogen

regulator of G-protein signaling 17 recombinant protein epitope signature tag (PrEST)

Application

All Prestige Antibodies Powered by Atlas Antibodies are developed and validated by the Human Protein Atlas (HPA) project and as a result, are supported by the most extensive characterization in the industry.

The Human Protein Atlas project can be subdivided into three efforts: Human Tissue Atlas, Cancer Atlas, and Human Cell Atlas. The antibodies that have been generated in support of the Tissue and Cancer Atlas projects have been tested by immunohistochemistry against hundreds of normal and disease tissues and through the recent efforts of the Human Cell Atlas project, many have been characterized by immunofluorescence to map the human proteome not only at the tissue level but now at the subcellular level. These images and the collection of this vast data set can be viewed on the Human Protein Atlas (HPA) site by clicking on the Image Gallery link. We also provide Prestige Antibodies^® protocols and other useful information.

Features and Benefits

Prestige Antibodies^® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies^® to other proteins are due to a thorough selection of antigen regions, affinity purification, and stringent selection. Prestige antigen controls are available for every corresponding Prestige Antibody and can be found in the linkage section.

Every Prestige Antibody is tested in the following ways:

IHC tissue array of 44 normal human tissues and 20 of the most common cancer type tissues.
Protein array of 364 human recombinant protein fragments.

Physical form

Solution in phosphate buffered saline, pH 7.2, containing 40% glycerol and 0.02% sodium azide.

Other Notes

Corresponding Antigen APREST73811

Legal Information

Prestige Antibodies is a registered trademark of Merck KGaA, Darmstadt, Germany

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Show Differences

1 of 1

This Item	HPA056493	SAB2109177	HPA055060
Sigma-Aldrich HPA022276 Anti-RGS17 antibody produced in rabbit	Sigma-Aldrich HPA056493 Anti-RGS17 antibody produced in rabbit	Sigma-Aldrich SAB2109177 Anti-RPS17 antibody produced in rabbit	Sigma-Aldrich HPA055060 Anti-RPS17 antibody produced in rabbit
Quality Level 100	Quality Level 100	Quality Level -	Quality Level 100
antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody	antibody form affinity isolated antibody
conjugate unconjugated	conjugate unconjugated	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
product line Prestige Antibodies^® Powered by Atlas Antibodies	product line Prestige Antibodies^® Powered by Atlas Antibodies	product line -	product line Prestige Antibodies^® Powered by Atlas Antibodies
technique(s) immunohistochemistry: 1:50-1:200, western blot: 0.04-0.4 μg/mL	technique(s) immunofluorescence: 0.25-2 μg/mL	technique(s) western blot: 1 μg/mL	technique(s) immunoblotting: 0.04-0.4 μg/mL, immunofluorescence: 0.25-2 μg/mL, immunohistochemistry: 1:200-1:500

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number

R09100

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RGS17/RGSZ2, a novel regulator of Gi/o, Gz, and Gq signaling.

Helen Mao et al.

The Journal of biological chemistry, 279(25), 26314-26322 (2004-04-21)

To identify novel regulators of Galpha(o), the most abundant G-protein in brain, we used yeast two-hybrid screening with constitutively active Galpha(o) as bait and identified a new regulator of G-protein signaling (RGS) protein, RGS17 (RGSZ2), as a novel human member

Global Trade Item Number

SKU	GTIN
HPA022276-100UL	04061835729210
HPA022276-25UL	04061842882052

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