(Aminomethyl)phosphonic acid

Name: (Aminomethyl)phosphonic acid
Brand: SIAL
Price: 86 USD
Availability: InStock

PESTANAL^®, analytical standard

Synonym(s):

AMPA

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About This Item

Linear Formula:

NH₂CH₂P(O)(OH)₂

CAS Number:

1066-51-9

Molecular Weight:

111.04

UNSPSC Code:

77101502

NACRES:

NA.24

PubChem Substance ID:

329747650

MDL number:

MFCD00008105

Beilstein/REAXYS Number:

1701219

Key Documents

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InChI

1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)

InChI key

MGRVRXRGTBOSHW-UHFFFAOYSA-N

SMILES string

NCP(O)(O)=O

grade

analytical standard

product line

PESTANAL^®

assay

≥98.0% (TLC)

shelf life

limited shelf life, expiry date on the label

impurities

≤3.0% water (calc. from elemental analysis)

application(s)

agriculture
environmental

format

neat

Quality Level

100

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1 of 4

This Item	43952	106615	324817
Supelco 05164 (Aminomethyl)phosphonic acid	Supelco 43952 (Aminomethyl)phosphonic acid	Sigma-Aldrich 106615 2,2-Bis(hydroxymethyl)propionic acid	Sigma-Aldrich 324817 (Aminomethyl)phosphonic acid
format neat	format -	format -	format -
assay ≥98.0% (TLC)	assay -	assay 98%	assay 99%
grade analytical standard	grade certified reference material, TraceCERT^®	grade -	grade -
product line PESTANAL^®	product line TraceCERT^®	product line -	product line -
shelf life limited shelf life, expiry date on the label	shelf life limited shelf life, expiry date on the label	shelf life -	shelf life -
impurities ≤3.0% water (calc. from elemental analysis)	impurities -	impurities -	impurities -

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Network compensation of cyclic GMP-dependent protein kinase II knockout in the hippocampus by Ca2+-permeable AMPA receptors.

Seonil Kim et al.

Proceedings of the National Academy of Sciences of the United States of America, 112(10), 3122-3127 (2015-02-26)

Gene knockout (KO) does not always result in phenotypic changes, possibly due to mechanisms of functional compensation. We have studied mice lacking cGMP-dependent kinase II (cGKII), which phosphorylates GluA1, a subunit of AMPA receptors (AMPARs), and promotes hippocampal long-term potentiation

The rostromedial tegmental nucleus modulates behavioral inhibition following cocaine self-administration in rats.

Mary L Huff et al.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(4), 861-873 (2014-09-27)

Recent findings suggest that the mesolimbic dopamine neurons, known to promote cocaine-seeking behavior, are strongly inhibited by a newly characterized region of the midbrain known as the rostromedial tegmental nucleus (RMTg). The RMTg appears to be involved in generating reward-prediction

The role of the lateral habenula in punishment.

Philip Jean-Richard Dit Bressel et al.

PloS one, 9(11), e111699-e111699 (2014-11-05)

The lateral habenula (LHb) is a small epithalamic structure that projects via the fasciculus retroflexus to the midbrain. The LHb is known to modulate midbrain dopamine (DA) neurons, including inhibition of ventral tegmental area (VTA) neurons via glutamatergic excitation of

Ketamine-induced antidepressant effects are associated with AMPA receptors-mediated upregulation of mTOR and BDNF in rat hippocampus and prefrontal cortex.

W Zhou et al.

European psychiatry : the journal of the Association of European Psychiatrists, 29(7), 419-423 (2013-12-11)

Ketamine exerts fast acting, robust, and lasting antidepressant effects in a sub-anesthetic dose, however, the underlying mechanisms are still not fully elucidated. Recent studies have suggested that ketamine's antidepressant effects are probably attributed to the activation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)

Systems reconsolidation reveals a selective role for the anterior cingulate cortex in generalized contextual fear memory expression.

Einar Ö Einarsson et al.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 40(2), 480-487 (2014-08-06)

After acquisition, hippocampus-dependent memories undergo a systems consolidation process, during which they become independent of the hippocampus and dependent on the anterior cingulate cortex (ACC) for memory expression. However, consolidated remote memories can become transiently hippocampus-dependent again following memory reactivation.

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