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Sigma-Aldrich

(3-Acrylamidopropyl)trimethylammonium chloride solution

75 wt. % in H2O

Synonym(s):

(Acrylamidopropyl)trimethylammonium chloride, Acryloylaminopropyltrimethylammonium chloride, Trimethyl(3-acrylamidopropyl)ammonium chloride

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About This Item

Linear Formula:
H2C=CHCONH(CH2)3N(CH3)3Cl
CAS Number:
Molecular Weight:
206.71
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

contains

3,000 ppm monomethyl ether hydroquinone as stabilizer

concentration

75 wt. % in H2O

refractive index

n20/D 1.4848

density

1.11 g/mL at 25 °C

storage temp.

2-8°C

SMILES string

[Cl-].C[N+](C)(C)CCCNC(=O)C=C

InChI

1S/C9H18N2O.ClH/c1-5-9(12)10-7-6-8-11(2,3)4;/h5H,1,6-8H2,2-4H3;1H

InChI key

OEIXGLMQZVLOQX-UHFFFAOYSA-N

General description

(3-Acrylamidopropyl)trimethylammonium chloride(APTAC) is a quaternary ammonium cationic monomer with high water solubility. It undergoes rapid cationic polymerization due to the presence of a permanent positive charge. It is utilized in the field of stimuli-responsive coatings, biosensors, drug delivery systems, medical devices, contact lenses, dental composites, wound healing, ion-exchange membranes for water treatment, and polymer 3Dscaffolds for tissue engineering.

Application

(3-Acrylamidopropyl)trimethylammonium chloride solution can be used:



  • As a cationic monomer to synthesize polyampholyte hydrogels (PAHs). These hydrogels show pH-responsive and ionic strength-responsive behavior and are suitable for application in smart coatings and biosensors.
  • As a monomer to prepare poly(APTAC) ion exchange membranes with high surface porosity, for the removal of Cu(II), Cr(VI), and As(V) ions from water.
  • As a precursor to fabricate cartilage mimetic polymer scaffolds that can be used in cartilage regeneration and replacement.

hcodes

Hazard Classifications

Aquatic Chronic 3

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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Emerging polymeric material strategies for cartilage repair
Connor J Demott and Melissa A Grunlan
Journal of materials chemistry. B, 10, 9578-9589 (2022)
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Macromolecular rapid communications, 41(21), e2000175-e2000175 (2020-08-18)
Contact lenses are medical devices commonly used to correct refractive errors and to maintain ocular health. Microorganisms such as bacteria that grow on the lens surface cause irritation to the eyes and can even cause loss of vision. In this
Junyi Li et al.
Journal of environmental sciences (China), 91, 177-188 (2020-03-17)
Excessive nitrate (NO3-) is among the most problematic surface water and groundwater pollutants. In this study, a type of magnetic cationic hydrogel (MCH) is employed for NO3- adsorption and well characterized herein. Its adsorption capacity is considerably pH-dependent and achieves
Novel biodegradable flocculanting agents based on pullulan
Ghimici L, et al.
Journal of Hazardous Materials, 181(1-3), 351-358 (2010)
Sarah Jurjevec et al.
Journal of colloid and interface science, 575, 480-488 (2020-05-16)
Macroporous polyampholyte hydrogels, simultaneously bearing both the anionic and cationic groups, demonstrate immense promise over the one-sign charged polyelectrolytes, owing to a unique phenomenon known as the ˝anti-polyelectrolyte˝ effect. Thus, they are extremely promising materials, since they remain solvated and

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