Key Documents

Sucrose

Name: Sucrose
Brand: SIGMA

Molecular Biology, ≥99.5% (GC)

Synonym(s):

α-D-Glc-(1→2)-β-D-Fru, α-D-Glucopyranosyl β-D-fructofuranoside, β-D-Fructofuranosyl-α-D-glucopyranoside, D(+)-Saccharose, Sugar

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About This Item

Empirical Formula (Hill Notation):

C₁₂H₂₂O₁₁

CAS Number:

57-50-1

Molecular Weight:

342.30

UNSPSC Code:

12352201

NACRES:

NA.31

PubChem Substance ID:

24899423

EC Number:

200-334-9

Beilstein/REAXYS Number:

90825

MDL number:

MFCD00006626

Pricing and availability is not currently available.

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biological source

sugar cane

Quality Level

300

grade

Molecular Biology

assay

≥99.5% (GC)

form

crystals

technique(s)

HPLC: suitable, cryopreservation: suitable, electron microscopy: suitable, enzyme immunoassay: suitable, gas chromatography (GC): suitable, immunohistochemistry: suitable

impurities

≤0.1% free glucose

color

white

useful pH range

5.5-7 (25 °C, 342 g/L)

mp

185-187 °C (lit.)

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Related Categories

Biochemicals

Carbohydrates for Biochemical Research

Cell Culture Supplements & Reagents

Chemical Biology

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Show Differences

1 of 1

This Item	S5016	84100	1.07651
Sigma-Aldrich S0389 Sucrose	Sigma-Aldrich S5016 Sucrose	Millipore 84100 Sucrose	Millipore 1.07651 Sucrose
biological source sugar cane	biological source sugar cane	biological source -	biological source -
grade Molecular Biology	grade ACS reagent	grade ACS reagent	grade -
technique(s) HPLC: suitable, electron microscopy: suitable, gas chromatography (GC): suitable, cryopreservation: suitable, immunohistochemistry: suitable, enzyme immunoassay: suitable	technique(s) HPLC: suitable, cryopreservation: suitable, immunohistochemistry: suitable	technique(s) -	technique(s) -
assay ≥99.5% (GC)	assay -	assay ≥99.0% (HPLC)	assay -
solubility H₂O: soluble 50 g + 50 mL	solubility soluble 342 g/L at 20 °C (completely)	solubility H₂O: 0.1 g/mL, clear, colorless	solubility -
Quality Level 300	Quality Level 300	Quality Level 200	Quality Level 200

General description

Sucrose, a disaccharide composed of glucose and fructose, serves as an energy source in various biological processes. In cell biology, sucrose acts as a cryoprotectant, preserving cell viability during freezing and thawing. It is also added as a supplement in culture media, aiding in maintaining osmotic balance and enhancing cell survival.In molecular biology, sucrose is crucial in gradient solutions for DNA and RNA purification and in density centrifugation for organelle separation.

Application

Sucrose has been used:

to perform cryoprotection for kidney tissues
as a component in the solid germination medium to germinate pollen grains
in the triphenyl-tetrazolium chloride (TTC) test to check the viability of pollen grains
in the cryoprotection of fixed brain tissues for immunohistochemistry

Biochem/physiol Actions

Sucrose is used as a transport and storage molecule in most plants due to its limited chemical reactivity. It can be used to prepare density gradients for the separation of cell/organelle. Sucrose can be used in the plant, insect, and bacterial culture media as a supplement. In addition, sucrose can also be used in several enzymatic assays.

Features and Benefits

Ideal for Molecular Biology, Cell Biology and Biochemical research
Tested to confirm low levels of heavy metal contamination, ensuring suitability for various applications
Tested for DNase, RNase, and proteases
Molecular biology grade sucrose, sourced from sugar cane

Other Notes

2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research

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To gain a comprehensive understanding of our extensive range of Disaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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c-Src drives intestinal regeneration and transformation.

Julia B Cordero et al.

The EMBO journal, 33(13), 1474-1491 (2014-05-03)

The non-receptor tyrosine kinase c-Src, hereafter referred to as Src, is overexpressed or activated in multiple human malignancies. There has been much speculation about the functional role of Src in colorectal cancer (CRC), with Src amplification and potential activating mutations

Sucrose for procedural pain management in infants.

Denise Harrison et al.

Pediatrics, 130(5), 918-925 (2012-10-10)

The use of oral sucrose has been the most extensively studied pain intervention in newborn care to date. More than 150 published studies relating to sweet-taste-induced calming and analgesia in human infants have been identified, of which 100 (65%) include

Induced over-expression of AtDREB2A CA improves drought tolerance in sugarcane.

Rafaela Ribeiro Reis et al.

Plant science : an international journal of experimental plant biology, 221-222, 59-68 (2014-03-25)

Drought is one of the most challenging agricultural issues limiting sustainable sugarcane production and, in some cases, yield losses caused by drought are nearly 50%. DREB proteins play vital regulatory roles in abiotic stress responses in plants. The transcription factor

Obesity in aging exacerbates blood-brain barrier disruption, neuroinflammation, and oxidative stress in the mouse hippocampus: effects on expression of genes involved in beta-amyloid generation and Alzheimer's disease.

Zsuzsanna Tucsek et al.

The journals of gerontology. Series A, Biological sciences and medical sciences, 69(10), 1212-1226 (2013-11-26)

There is growing evidence that obesity has deleterious effects on the brain and cognitive function in the elderly population. However, the specific mechanisms through which aging and obesity interact to promote cognitive decline remain unclear. To test the hypothesis that

Daily heat stress treatment rescues denervation-activated mitochondrial clearance and atrophy in skeletal muscle.

Yuki Tamura et al.

The Journal of physiology, 593(12), 2707-2720 (2015-04-23)

Traumatic nerve injury or nerve disease leads to denervation and severe muscle atrophy. Recent evidence shows that mitochondrial loss could be a key mediator of skeletal muscle atrophy. Here, we show that daily heat stress treatment rescues denervation-induced loss of

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Global Trade Item Number

SKU	GTIN
S0389-5KG	04061835549047
S0389-500G	04061835549030
S0389-1KG	04061835549023

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