Upon thawing, this solution may be aliquoted and refrozen one time for long term storage, up to the lot specific expiration date. The thawed solution is stable for up to 1 week if stored refrigerated and up to 3 days in a culture medium at 37°C.
P4333
Penicillin-Streptomycin
liquid, non-animal origin, suitable for cell culture, BioReagent
Penicillin-Streptomycin
Synonym(s):
Pen-Strep
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| 20 mL | Estimated to ship onMarch 23, 2026fromMILWAUKEE | $17.30 | |
| 100 mL | Estimated to ship onMarch 23, 2026fromMILWAUKEE | $36.30 |
About This Item
UNSPSC Code:
12352207
NACRES:
NA.76
Product Name
Penicillin-Streptomycin, Solution stabilized, with 10,000 units penicillin and 10 mg streptomycin/mL, 0.1 μm filtered, BioReagent, suitable for cell culture
Quality Level
sterility
0.1 μm filtered
product line
BioReagent
form
liquid
feature
subscription eligible
concentration
100 ×
technique(s)
cell culture | mammalian: suitable
impurities
endotoxin, tested
antibiotic activity spectrum
Gram-negative bacteria, Gram-positive bacteria
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Related Categories
1 of 1
This Item | |||
|---|---|---|---|
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria | antibiotic activity spectrum Gram-negative bacteria, Gram-positive bacteria |
| mode of action protein synthesis | interferes, cell wall synthesis | interferes | mode of action cell wall synthesis | interferes, protein synthesis | interferes | mode of action cell wall synthesis | interferes, protein synthesis | interferes | mode of action cell wall synthesis | interferes, protein synthesis | interferes |
| product line BioReagent | product line BioReagent | product line BioReagent | product line - |
| Quality Level 300 | Quality Level 300 | Quality Level 300 | Quality Level 100 |
| form liquid | form liquid | form liquid | form lyophilized (clear, colorless solution after reconstitution) |
General description
Penicillin Streptomycin solution, also known as Pen Strep, is the most commonly used antibiotic solution for the culture of mammalian cells. Penicillin Streptomycin solution is used to maintain sterile conditions during cell culture, and they show few adverse effects on the cultured cells.[1]
Application
Penicillin-Streptomycin is used to supplement cell culture media to control bacterial contamination. It is recommended for use in cell culture applications at 10 mL/L.
Penicillin streptomycin solution has been used as a supplement in different types of media, including RGC (retinal ganglion cells) culture,[2] α-MEM (minimum essential medium) growth medium,[3] Dulbecco′s modified Eagle′s medium (DMEM)/nutrient mixture F-12 Ham,[4] DMEM[5] and DMEM/F-12 + GlutaMax.[6]
Penicillin streptomycin solution has been used as a supplement in different types of media, including RGC (retinal ganglion cells) culture,[2] α-MEM (minimum essential medium) growth medium,[3] Dulbecco′s modified Eagle′s medium (DMEM)/nutrient mixture F-12 Ham,[4] DMEM[5] and DMEM/F-12 + GlutaMax.[6]
Other Notes
20ml,100ml
Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.Storage class (TRGS 510): Non Combustible Liquids
This product is formulated to contain 10,000 units penicillin and 10 mg streptomycin/mL solubilized in a proprietary citrate buffer.
related product
Product No.
Description
Pricing
Storage Class
12 - Non Combustible Liquids
wgk
WGK 2
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ZhiMin Wang et al.
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J H Martínez-Liarte et al.
Pigment cell research, 8(2), 83-88 (1995-04-01)
Penicillin and streptomycin, the most widely used antibiotics in mammalian cell cultures, caused a moderate stimulation in dopa oxidase and tyrosine hydroxylase activities, but a slight inactivation in the dopachrome tautomerase activity of B16/F10 melanoma cells at the routine concentration
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Journal of laboratory automation, 18(3), 212-228 (2012-09-28)
A microfluidic component library for building systems driving parallel or serial microfluidic-based assays is presented. The components are a miniaturized eight-channel peristaltic pump, an eight-channel valve, sample-to-waste liquid management, and interconnections. The library of components was tested by constructing various
184: Toxic effects of antibiotics routinely used in cell culture on primary cultures of dissociated mouse brain cells.
Ammon F
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We have previously shown that overexpressing subunits of the iron-binding protein ferritin can rescue the toxicity of the amyloid β (Aβ) peptide in our Drosophila model system. These data point to an important pathogenic role for iron in Alzheimer disease.
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| P4333-100ML | 04061838447333 |
| P4333-20ML | 04061838447340 |
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How long can you store Pen/Strep: cat No.P4333 at 4C?
1 answer-
Helpful?
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Is it possible to thaw it before use by taking it out of the -20°C storage? If so, what is the recommended method for thawing?
1 answer-
It is best to aliquot it, keep the stock at -20°C, and take out the needed amount, leaving it in the fridge (4°C) overnight for use the next day. Warming it before use in a warm water bath is not recommended.
Helpful?
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Do you label any products as GMP compliant?
1 answer-
Product P4333 is not GMP. The penicillin-streptomycin products currently offered are supplied for research and development applications.
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