ZP4
zona pellucida glycoprotein 4
Synonyms:
ZBP, ZP1, ZPB, Zp-4
Species:
Human ZP4 (57829), Rat Zp4 (282833), naked mole-rat Zp4 (101719754), Domestic Rabbit ZP4 (100009131), domestic cat ZP4 (493791), chicken ZP4 (395692), sheep ZP4 (101117046), dog ZP4 (442977), cow ZP4 (280965), domestic guinea pig Zp4 (100731580)
UniProtKB ID:
Gene ID:
- Human(57829) Summary: The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. [provided by RefSeq, Jul 2008]
- Rat(282833) zona pellucida glycoprotein 4
- naked mole-rat(101719754) zona pellucida glycoprotein 4
- Domestic Rabbit(100009131) zona pellucida glycoprotein 4
- domestic cat(493791) zona pellucida glycoprotein 4
- chicken(395692) zona pellucida glycoprotein 4
- sheep(101117046) zona pellucida glycoprotein 4
- dog(442977) zona pellucida glycoprotein 4
- cow(280965) zona pellucida glycoprotein 4
- domestic guinea pig(100731580) zona pellucida glycoprotein 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ZP4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-ZP4 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
ELISA
western blot
western blot