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Merck

WASF1

WAS protein family, member 1

Synonyms:
SCAR1, WAVE, WAVE1
Species:
UniProtKB ID:
Gene ID:
  • Human(8936) Summary: The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP)-family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(83767) WAS protein family, member 1
  • Rat(294568) WAS protein family, member 1
  • Horse(100066751) WAS protein family, member 1
  • domestic cat(101083083) WAS protein family, member 1
  • dog(475024) WAS protein family, member 1
  • chicken(421761) WAS protein family, member 1
  • naked mole-rat(101705685) WAS protein family, member 1
  • domestic guinea pig(100716147) WAS protein family, member 1
  • sheep(101112488) WAS protein family, member 1
  • cow(531488) WAS protein family, member 1

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-WASF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-WAVE-1 Antibody, clone K91/36, clone K91/36, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
Anti-WAVE1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-WAVE antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
microarray
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Wasf1,
Species
mouse
MISSION® esiRNA, targeting human WASF1,
Species
human