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Merck

UGT1A6

UDP glucuronosyltransferase 1 family, polypeptide A6

Synonyms:
GNT1, HLUGP, HLUGP1, UDPGT, UDPGT 1-6, UGT1, UGT1A6S, UGT1F
Species:
Human UGT1A6 (54578), Rat Ugt1a6 (113992), cow UGT1A6 (286792), sheep UGT1A6 (100534643), dog UGT1A6 (403629), domestic cat UGT1A6 (100750222), domestic guinea pig Ugt1a6 (100731122), Zebrafish ugt1a6 (100384896), naked mole-rat Ugt1a6 (101707823)
UniProtKB ID:
P19224, A6NKK6, Q96TE7
Gene ID:
  • Human(54578) Summary: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenolic and planar compounds. Alternative splicing in the unique 5' end of this gene results in two transcript variants. [provided by RefSeq, Jul 2008]
  • Rat(113992) UDP glucuronosyltransferase 1 family, polypeptide A6
  • cow(286792) UDP glucuronosyltransferase 1 family, polypeptide A6
  • sheep(100534643) UDP glucuronosyltransferase 1 family, polypeptide A6
  • dog(403629) UDP glucuronosyltransferase 1 family, polypeptide A6
  • domestic cat(100750222) UDP-glucuronosyltransferase 1A6
  • domestic guinea pig(100731122) UDP glucuronosyltransferase 1 family, polypeptide A6
  • Zebrafish(100384896) UDP glucuronosyltransferase 1 family, polypeptide A6
  • naked mole-rat(101707823) UDP glucuronosyltransferase 1 family, polypeptide A6

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2102641
Anti-UGT1A6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
dog, guinea pig, horse, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
HPA056023
Anti-Ugt1A6 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
HPA054065
Anti-UGT1A6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
WH0054578M3
Monoclonal Anti-UGT1A6 antibody produced in mouse, clone 4A10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA