UBE2K
ubiquitin-conjugating enzyme E2K
E2-25K, HIP2, HYPG, LIG, UBC1
Human UBE2K (3093), Mouse Ube2k (53323), Rat Ube2k (289623), domestic guinea pig Ube2k (100716372), cow UBE2K (281225), sheep UBE2K (101109971), dog UBE2K (609531), domestic cat UBE2K (101081979), chicken UBE2K (428787)
- Human(3093) Summary: The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(53323) ubiquitin-conjugating enzyme E2K
- Rat(289623) ubiquitin-conjugating enzyme E2K
- domestic guinea pig(100716372) ubiquitin-conjugating enzyme E2K
- cow(281225) ubiquitin-conjugating enzyme E2K
- sheep(101109971) ubiquitin-conjugating enzyme E2K
- dog(609531) ubiquitin-conjugating enzyme E2K
- domestic cat(101081979) ubiquitin-conjugating enzyme E2K
- chicken(428787) ubiquitin-conjugating enzyme E2K
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