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Merck

TSLP

thymic stromal lymphopoietin

Synonyms:
Species:
Human TSLP (85480), Mouse Tslp (53603), Rat Tslp (688621), domestic cat TSLP (101085857), dog TSLP (607671), domestic guinea pig Tslp (101788673), Horse TSLP (100302635)
UniProtKB ID:
Q969D9, Q8IW99
Gene ID:
  • Human(85480) Summary: This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
  • Mouse(53603) thymic stromal lymphopoietin
  • Rat(688621) thymic stromal lymphopoietin
  • domestic cat(101085857) thymic stromal lymphopoietin
  • dog(607671) thymic stromal lymphopoietin
  • domestic guinea pig(101788673) thymic stromal lymphopoietin
  • Horse(100302635) thymic stromal lymphopoietin

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ELISA

Product Number
Description
Species
RAB0504
Mouse TSLP ELISA Kit, for serum, plasma and cell culture supernatant,
Species
mouse
RAB0503
Human TSLP ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
PRS4025
Anti-TSLP (ab3) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
PRS4021
Anti-TSLP (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
ABT330
Anti-TSLP Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry
western blot
ABF113
Anti-TSLP Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human
Application
immunohistochemistry
western blot
PRS4023
Anti-TSLP (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP4896
TSLP human, recombinant, expressed in E. coli, ≥97% (SDS-PAGE), ≥97% (HPLC),
Species
human

esiRNA

Product Number
Description
Species
EHU075571
MISSION® esiRNA, targeting human TSLP,
Species
human