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TNK1

tyrosine kinase, non-receptor, 1

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(8711) Summary: The protein encoded by this gene belongs to the tyrosine protein kinase family. Tyrosine protein kinases are important regulators of intracellular signal transduction pathways, mediating cellular proliferation, survival, and development. This gene is highly expressed in fetal tissues and at lower levels in few adult tissues, thus may function in signaling pathways utilized broadly during fetal development, and more selectively in adult tissues. It plays a negative regulatory role in the Ras-Raf1-MAPK pathway, and knockout mice have been shown to develop spontaneous tumors, suggesting a role as a tumor suppressor gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(83813) tyrosine kinase, non-receptor, 1
  • Rat(303247) tyrosine kinase, non-receptor, 1
  • dog(489470) tyrosine kinase, non-receptor, 1
  • domestic guinea pig(100735628) tyrosine kinase, non-receptor, 1
  • naked mole-rat(101721050) tyrosine kinase, non-receptor, 1
  • Horse(100061776) tyrosine kinase, non-receptor, 1
  • cow(510356) tyrosine kinase, non-receptor, 1
  • domestic cat(101096181) tyrosine kinase, non-receptor, 1
  • sheep(101119833) tyrosine kinase, non-receptor, 1

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Phosphotyrosine TNK1 / Non-receptor Tyrosine-protein Kinase TNK1 ELISA Kit, ,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-TNK1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-TNK1 Antibody, from rabbit,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human TNK1,
Species
human