TNFRSF10C
tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
Synonyms:
CD263, DCR1, DCR1-TNFR, LIT, TRAIL-R3, TRAILR3, TRID
Species:
UniProtKB ID:
Gene ID:
- Human(8794) Summary: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008]
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Custom Gene Products
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ELISA
Product Number
Description
Species
Human TRAIL R3 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Species
human
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DCR1 (ab2) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Monoclonal Anti-CD263-APC antibody produced in mouse, clone TRAIL-R3-02,
Species Reactivity
Application
flow cytometry
Anti-DCR1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunocytochemistry
western blot
immunocytochemistry
western blot
Monoclonal Anti-CD263-PE antibody produced in mouse, clone TRAIL-R3-02, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
Monoclonal Anti-CD263, azide free antibody produced in mouse, clone TRAIL-R3-02, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
flow cytometry
esiRNA
Product Number
Description
Species