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STAU1

staufen double-stranded RNA binding protein 1

Synonyms:
STAU
Species:
UniProtKB ID:
Gene ID:
  • Human(6780) Summary: Staufen is a member of the family of double-stranded RNA (dsRNA)-binding proteins involved in the transport and/or localization of mRNAs to different subcellular compartments and/or organelles. These proteins are characterized by the presence of multiple dsRNA-binding domains which are required to bind RNAs having double-stranded secondary structures. The human homologue of staufen encoded by STAU, in addition contains a microtubule- binding domain similar to that of microtubule-associated protein 1B, and binds tubulin. The STAU gene product has been shown to be present in the cytoplasm in association with the rough endoplasmic reticulum (RER), implicating this protein in the transport of mRNA via the microtubule network to the RER, the site of translation. Five transcript variants resulting from alternative splicing of STAU gene and encoding three isoforms have been described. Three of these variants encode the same isoform, however, differ in their 5'UTR. [provided by RefSeq, Jul 2008]
  • Mouse(20853) staufen (RNA binding protein) homolog 1 (Drosophila)
  • Rat(84496) staufen double-stranded RNA binding protein 1
  • domestic guinea pig(100733497) staufen double-stranded RNA binding protein 1
  • naked mole-rat(101704614) staufen double-stranded RNA binding protein 1
  • Zebrafish(334440) staufen, RNA binding protein, homolog 1 (Drosophila)
  • chicken(419213) staufen, RNA binding protein, homolog 1 (Drosophila)
  • domestic cat(101080626) staufen, RNA binding protein, homolog 1 (Drosophila)
  • dog(477258) staufen, RNA binding protein, homolog 1 (Drosophila)
  • sheep(101120429) staufen, RNA binding protein, homolog 1 (Drosophila)
  • cow(513944) staufen double-stranded RNA binding protein 1
  • Horse(100056924) staufen, RNA binding protein, homolog 1 (Drosophila)

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Antibodies

Product Number
Description
Species Reactivity
Application
ANTI-STAU1 antibody produced in mouse, clone 4D6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
Anti-STAU1 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-STAU1 antibody produced in mouse, clone 3D8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot
Anti-Staufen Antibody, clone 8J5A6, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
Anti-STAU1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Stau1,
Species
mouse
MISSION® esiRNA, targeting human STAU1,
Species
human