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SRSF1

serine/arginine-rich splicing factor 1

Synonyms:
ASF, SF2, SF2p33, SFRS1, SRp30a
Species:
UniProtKB ID:
Gene ID:
  • Human(6426) Summary: This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 13. [provided by RefSeq, Sep 2010]
  • Mouse(110809) serine/arginine-rich splicing factor 1
  • Rat(689890) serine/arginine-rich splicing factor 1
  • dog(609693) serine/arginine-rich splicing factor 1
  • chicken(772264) serine/arginine-rich splicing factor 1
  • sheep(101121021) serine/arginine-rich splicing factor 1
  • domestic guinea pig(100721786) serine/arginine-rich splicing factor 1
  • Horse(100056763) serine/arginine-rich splicing factor 1
  • naked mole-rat(101699866) serine/arginine-rich splicing factor 1
  • cow(615796) serine/arginine-rich splicing factor 1
  • domestic cat(101100012) serine/arginine-rich splicing factor 1

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ASF-1 (SF2) Antibody, clone AK96, clone AK96, from mouse,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-SRp30a (SF2) Antibody, from rabbit,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
western blot
Anti-SRSF1/SF2/ASF antibody produced in rabbit, ,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-ASF-1 Antibody, clone AK-96, clone AK-96, from mouse,
Species Reactivity
human
Application
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-SRSF1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

Proteins

Product Number
Description
Species
Arginine Splicing Factor, His tagged human, recombinant, expressed in insect cells, ≥85% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SRSF1,
Species
human