SPR
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
Synonyms:
SDR38C1
Species:
Human SPR (6697), Mouse Spr (20751), Rat Spr (29270), fruit fly Spr (247245), fruit fly spr (252698), fruit fly SPR (31463), chicken SPR (425255), dog SPR (483118), domestic cat SPR (101101210), cow SPR (533836) ...More
UniProtKB ID:
Gene ID:
- Human(6697) Summary: This gene encodes an aldo-keto reductase that catalyzes the NADPH-dependent reduction of pteridine derivatives and is important in the biosynthesis of tetrahydrobiopterin (BH4). Mutations in this gene result in DOPA-responsive dystonia due to sepiaterin reductase deficiency. A pseudogene has been identified on chromosome 1. [provided by RefSeq, Jul 2008]
- Mouse(20751) sepiapterin reductase
- Rat(29270) sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
- fruit fly(247245) Spread
- fruit fly(252698) spread wings
- fruit fly(31463) Sex peptide receptor
- chicken(425255) sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
- dog(483118) sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
- domestic cat(101101210) sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
- cow(533836) sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
- sheep(101111439) sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
- domestic guinea pig(100719412) sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
- naked mole-rat(101713942) sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-SPR antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-SPR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-SPR, (C-terminal) antibody produced in mouse, clone 4F2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
esiRNA
Product Number
Description
Species