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Merck

SPANXC

SPANX family, member C

Synonyms:
C, CT11.3, CTp11, SPANX-C
Species:
UniProtKB ID:
Gene ID:
  • Human(64663) Summary: Temporally regulated transcription and translation of several testis-specific genes is required to initiate the series of molecular and morphological changes in the male germ cell lineage necessary for the formation of mature spermatozoa. This gene is a member of the SPANX family, which is located in a gene cluster on chromosome X. The SPANX genes encode differentially expressed testis-specific proteins that localize to various subcellular compartments. This particular gene encodes a protein that localizes to the nucleus and is expressed in highly metastatic cell lines, making the protein a potential diagnostic and prognostic marker. The protein belongs to a family of cancer/testis antigens and represents a potential target for cancer immunotherapy. [provided by RefSeq, Jul 2008]

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SPANXC (AB2) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-SPANXC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SPANXC,
Species
human