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SLC22A5

solute carrier family 22 (organic cation/carnitine transporter), member 5

Synonyms:
CDSP, OCTN2, OCTN2VT
Species:
UniProtKB ID:
Gene ID:
  • Human(6584) Summary: Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. The encoded protein is a plasma integral membrane protein which functions both as an organic cation transporter and as a sodium-dependent high affinity carnitine transporter. The encoded protein is involved in the active cellular uptake of carnitine. Mutations in this gene are the cause of systemic primary carnitine deficiency (CDSP), an autosomal recessive disorder manifested early in life by hypoketotic hypoglycemia and acute metabolic decompensation, and later in life by skeletal myopathy or cardiomyopathy. [provided by RefSeq, Jul 2008]
  • Mouse(20520) solute carrier family 22 (organic cation transporter), member 5
  • Rat(29726) solute carrier family 22 (organic cation/carnitine transporter), member 5
  • chicken(416328) solute carrier family 22 (organic cation transporter), member 5
  • chicken(101664718) solute carrier family 22 (organic cation/carnitine transporter), member 5
  • Horse(100072871) solute carrier family 22 (organic cation/carnitine transporter), member 5
  • domestic cat(101084417) solute carrier family 22 (organic cation/carnitine transporter), member 5
  • dog(608146) solute carrier family 22 (organic cation/carnitine transporter), member 5
  • Domestic Rabbit(100358417) solute carrier family 22 (organic cation/carnitine transporter), member 5
  • sheep(101122785) solute carrier family 22 (organic cation/carnitine transporter), member 5
  • cow(541266) solute carrier family 22 (organic cation/carnitine transporter), member 5
  • naked mole-rat(101720927) solute carrier family 22 (organic cation/carnitine transporter), member 5
  • domestic guinea pig(100719297) solute carrier family 22 (organic cation/carnitine transporter), member 5

Custom & Knockdown Gene Products

  • siRNA

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SLC22A5 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SLC22A5,
Species
human