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Merck

SF3B2

splicing factor 3b, subunit 2, 145kDa

Synonyms:
Cus1, SAP145, SF3B145, SF3b1, SF3b150
Species:
Human SF3B2 (10992), Mouse Sf3b2 (319322), Rat Sf3b2 (293671), naked mole-rat Sf3b2 (101702423), sheep SF3B2 (101112933), cow SF3B2 (531931), domestic cat SF3B2 (101081926), Horse SF3B2 (100052173), dog SF3B2 (476015), Zebrafish sf3b2 (570994)
UniProtKB ID:
Q13435, A8K485, B4DT19, Q7L4T5, Q7Z627, Q969K1, Q96CM6, Q9BWD2
Gene ID:
  • Human(10992) Summary: This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus. [provided by RefSeq, Jul 2008]
  • Mouse(319322) splicing factor 3b, subunit 2
  • Rat(293671) splicing factor 3b, subunit 2
  • naked mole-rat(101702423) splicing factor 3b, subunit 2, 145kDa
  • sheep(101112933) splicing factor 3b, subunit 2, 145kDa
  • cow(531931) splicing factor 3b, subunit 2, 145kDa
  • domestic cat(101081926) splicing factor 3b, subunit 2, 145kDa
  • Horse(100052173) splicing factor 3b, subunit 2, 145kDa
  • dog(476015) splicing factor 3b, subunit 2, 145kDa
  • Zebrafish(570994) splicing factor 3b, subunit 2
  • domestic guinea pig(100727105) splicing factor 3b, subunit 2, 145kDa

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA045028
Anti-SF3B2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
EMU024631
MISSION® esiRNA, targeting mouse Sf3b2,
Species
mouse
EHU061071
MISSION® esiRNA, targeting human SF3B2,
Species
human