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SEMA6D

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(80031) Summary: Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]
  • Mouse(214968) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • Rat(311384) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • domestic cat(101100893) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • sheep(101112064) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • Domestic Rabbit(100353114) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • domestic guinea pig(100715046) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • Horse(100055875) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • Zebrafish(406272) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • naked mole-rat(101723276) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • dog(478291) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • cow(518458) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
  • chicken(415430) sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

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ELISA

Product Number
Description
Species
Human Semaphorin 6D ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SEMA6D antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rabbit, rat
Application
western blot
Anti-SEMA6D antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Sema6d,
Species
mouse
MISSION® esiRNA, targeting human SEMA6D,
Species
human