RUNX3
runt-related transcription factor 3
Synonyms:
AML2, CBFA3, PEBP2aC
Species:
Human RUNX3 (864), Mouse Runx3 (12399), Rat Runx3 (156726), chicken RUNX3 (769687), Zebrafish runx3 (58127), naked mole-rat Runx3 (101726268), cow RUNX3 (617389), dog RUNX3 (487366), domestic cat RUNX3 (101080466), sheep RUNX3 (101119625) ...More
UniProtKB ID:
Gene ID:
- Human(864) Summary: This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(12399) runt related transcription factor 3
- Rat(156726) runt-related transcription factor 3
- chicken(769687) runt-related transcription factor 3
- Zebrafish(58127) runt-related transcription factor 3
- naked mole-rat(101726268) runt-related transcription factor 3
- cow(617389) runt-related transcription factor 3
- dog(487366) runt-related transcription factor 3
- domestic cat(101080466) runt-related transcription factor 3
- sheep(101119625) runt-related transcription factor 3
- Horse(100071400) runt-related transcription factor 3
- domestic guinea pig(100735006) runt-related transcription factor 3
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-RUNX3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-Runx3 Antibody, clone R3-5G4, clone R3-5G4, from mouse,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
western blot