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Merck

RBMXL2

RNA binding motif protein, X-linked-like 2

Synonyms:
HNRNPG-T, HNRNPGT, HNRPGT
Species:
Human RBMXL2 (27288), Mouse Rbmxl2 (76572), Rat Rbmxl2 (365344), cow RBMXL2 (617969)
UniProtKB ID:
O75526, Q6PEZ2, Q9NQU0
Gene ID:
  • Human(27288) Summary: This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two RRM domains that bind RNAs. This gene is intronless and is thought to be derived from a processed retroposon. However, unlike many retroposon-derived genes, this gene is not a pseudogene. The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator. It primarily localizes to the nuclei of meiotic spermatocytes. This gene is a candidate for autosomal male infertility. [provided by RefSeq, Jul 2008]
  • Mouse(76572) RNA binding motif protein, X-linked-like 2
  • Rat(365344) RNA binding motif protein, X-linked-like 2
  • cow(617969) RNA binding motif protein, X-linked-like 2

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0027288M1
Monoclonal Anti-HNRNPG-T antibody produced in mouse, clone 6F11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
HPA038912
Anti-RBMXL2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
HPA051842
Anti-RBMXL2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry

esiRNA

Product Number
Description
Species
EHU136741
MISSION® esiRNA, targeting human RBMXL2,
Species
human