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Merck

RASAL1

RAS protein activator like 1 (GAP1 like)

Synonyms:
RASAL
Species:
Human RASAL1 (8437), Mouse Rasal1 (19415), Rat Rasal1 (360814), dog RASAL1 (486277), chicken RASAL1 (771057), naked mole-rat Rasal1 (101697586), domestic guinea pig Rasal1 (100717596), Domestic Rabbit RASAL1 (100341044), cow RASAL1 (512872), sheep RASAL1 (101109393)
UniProtKB ID:
O95294, B7ZKM4, C9JFK5, F8VQX1, Q52M03, Q59H24, Q96CC7
Gene ID:
  • Human(8437) Summary: The protein encoded by this gene is member of the GAP1 family of GTPase-activating proteins. These proteins stimulate the GTPase activity of normal RAS p21 but not its oncogenic counterpart. Acting as a suppressor of RAS function, the protein enhances the weak intrinsic GTPase activity of RAS proteins resulting in the inactive GDP-bound form of RAS, thereby allowing control of cellular proliferation and differentiation. This particular family member contains domains which are characteristic of the GAP1 subfamily of RasGAP proteins but, in contrast to the other GAP1 family members, this protein is strongly and selectively expressed in endocrine tissues. Alternatively spliced transcript variants that encode different isoforms have been described [provided by RefSeq, Jul 2010]
  • Mouse(19415) RAS protein activator like 1 (GAP1 like)
  • Rat(360814) RAS protein activator like 1 (GAP1 like)
  • dog(486277) RAS protein activator like 1 (GAP1 like)
  • chicken(771057) RAS protein activator like 1 (GAP1 like)
  • naked mole-rat(101697586) RAS protein activator like 1 (GAP1 like)
  • domestic guinea pig(100717596) RAS protein activator like 1 (GAP1 like)
  • Domestic Rabbit(100341044) RAS protein activator like 1 (GAP1 like)
  • cow(512872) RAS protein activator like 1 (GAP1 like)
  • sheep(101109393) RAS protein activator like 1 (GAP1 like)
  • domestic cat(101088621) RAS protein activator like 1 (GAP1 like)

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB2500869
Anti-RASAL antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
HPA041650
Anti-RASAL1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
SAB2107693
Anti-RASAL1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
EMU036111
MISSION® esiRNA, targeting mouse Rasal1,
Species
mouse
EHU037111
MISSION® esiRNA, targeting human RASAL1,
Species
human