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Merck

PPP1R1B

protein phosphatase 1, regulatory (inhibitor) subunit 1B

Synonyms:
DARPP-32, DARPP32
Species:
Human PPP1R1B (84152), Mouse Ppp1r1b (19049), Rat Ppp1r1b (360616), cow PPP1R1B (282459), domestic cat PPP1R1B (101090972), dog PPP1R1B (608394), sheep PPP1R1B (101103077), Zebrafish ppp1r1b (100884132), chicken PPP1R1B (426639), naked mole-rat Ppp1r1b (101708486)
UniProtKB ID:
Q9UD71, Q547V9, Q547W0, Q9H7G1
Gene ID:
  • Human(84152) Summary: This gene encodes a bifunctional signal transduction molecule. Dopaminergic and glutamatergic receptor stimulation regulates its phosphorylation and function as a kinase or phosphatase inhibitor. As a target for dopamine, this gene may serve as a therapeutic target for neurologic and psychiatric disorders. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
  • Mouse(19049) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • Rat(360616) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • cow(282459) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • domestic cat(101090972) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • dog(608394) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • sheep(101103077) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • Zebrafish(100884132) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • chicken(426639) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • naked mole-rat(101708486) protein phosphatase 1, regulatory (inhibitor) subunit 1B
  • domestic guinea pig(100726824) protein phosphatase 1, regulatory (inhibitor) subunit 1B

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB4503329
Anti-DARPP-32 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
SAB4300150
Anti-phospho-PPP1R1B (pThr75) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
ZRB2260
Anti-DARPP-32 Antibody, clone 1D22 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
affinity binding assay
immunohistochemistry
western blot
SAB5702456
Anti-DARPP32 Antibody, clone 5T9G4, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot
AB9208
Anti-DARPP-32 Antibody, phosphoThr75, Chemicon®, from rabbit,
Species Reactivity
human, mouse
Application
western blot

Proteins

Product Number
Description
Species
AG657
DARPP-32, recombinant, His-tagged, ,
Species
human

esiRNA

Product Number
Description
Species
EHU146161
MISSION® esiRNA, targeting human PPP1R1B,
Species
human
EMU054931
MISSION® esiRNA, targeting mouse Ppp1r1b,
Species
mouse