Skip to Content
Merck

PNPLA6

patatin-like phospholipase domain containing 6

Synonyms:
NTE, NTEMND, SPG39, iPLA2delta, sws
Species:
Human PNPLA6 (10908), Mouse Pnpla6 (50767), Rat Pnpla6 (360753), Horse PNPLA6 (100060640), Zebrafish pnpla6 (386860), chicken PNPLA6 (425396), domestic guinea pig Pnpla6 (100714197), naked mole-rat Pnpla6 (101724286), cow PNPLA6 (767822), sheep PNPLA6 (101123119) ...More
UniProtKB ID:
Q8IY17, A6NGQ0, B4DFB9, B7Z7T2, F5H5K9, J3KQS3, O60859, Q86W58
Gene ID:
  • Human(10908) Summary: This gene encodes a phospholipase that deacetylates intracellular phosphatidylcholine to produce glycerophosphocholine. It is thought to function in neurite outgrowth and process elongation during neuronal differentiation. The protein is anchored to the cytoplasmic face of the endoplasmic reticulum in both neurons and non-neuronal cells. Mutations in this gene result in autosomal recessive spastic paraplegia, and the protein is the target for neurodegeneration induced by organophosphorus compounds and chemical warfare agents. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
  • Mouse(50767) patatin-like phospholipase domain containing 6
  • Rat(360753) patatin-like phospholipase domain containing 6
  • Horse(100060640) patatin-like phospholipase domain containing 6
  • Zebrafish(386860) patatin-like phospholipase domain containing 6
  • chicken(425396) patatin-like phospholipase domain containing 6
  • domestic guinea pig(100714197) patatin-like phospholipase domain containing 6
  • naked mole-rat(101724286) patatin-like phospholipase domain containing 6
  • cow(767822) patatin-like phospholipase domain containing 6
  • sheep(101123119) patatin-like phospholipase domain containing 6
  • dog(484993) patatin-like phospholipase domain containing 6
  • domestic cat(101097705) patatin-like phospholipase domain containing 6

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
HPA007522
Anti-PNPLA6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
SAB1402533
Monoclonal Anti-NTE, (C-terminal) antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
HPA064773
Anti-PNPLA6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
SAB2106745
Anti-PNPLA6 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot

esiRNA

Product Number
Description
Species
EMU050871
MISSION® esiRNA, targeting mouse Pnpla6,
Species
mouse
EHU057391
MISSION® esiRNA, targeting human PNPLA6,
Species
human