PHKA1
phosphorylase kinase, alpha 1 (muscle)
Synonyms:
PHKA
Species:
Human PHKA1 (5255), Mouse Phka1 (18679), Rat Phka1 (64561), dog PHKA1 (491956), sheep PHKA1 (101110737), domestic guinea pig Phka1 (100726293), Zebrafish phka1 (572183), cow PHKA1 (525990), cow PHKA1 (100336808), naked mole-rat Phka1 (101699364) ...More
UniProtKB ID:
Gene ID:
- Human(5255) Summary: Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation. The delta subunit mediates the dependence of the enzyme on calcium concentration. Mutations in this gene cause glycogen storage disease type 9D, also known as X-linked muscle glycogenosis. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene. A pseudogene has been found on chromosome 1.[provided by RefSeq, Feb 2010]
- Mouse(18679) phosphorylase kinase alpha 1
- Rat(64561) phosphorylase kinase, alpha 1
- dog(491956) phosphorylase kinase, alpha 1 (muscle)
- sheep(101110737) phosphorylase kinase, alpha 1 (muscle)
- domestic guinea pig(100726293) phosphorylase kinase, alpha 1 (muscle)
- Zebrafish(572183) phosphorylase kinase, alpha 1 (muscle)
- cow(525990) phosphorylase kinase, alpha 1 (muscle)
- cow(100336808) phosphorylase kinase, alpha 1 (muscle)
- naked mole-rat(101699364) phosphorylase kinase, alpha 1 (muscle)
- Horse(100051524) phosphorylase kinase, alpha 1 (muscle)
- chicken(422181) phosphorylase kinase, alpha 1 (muscle)
- domestic cat(101096789) phosphorylase kinase, alpha 1 (muscle)
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PHKA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry