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Merck

PHC2

polyhomeotic homolog 2 (Drosophila)

Synonyms:
EDR2, HPH2, PH2
Species:
Human PHC2 (1912), Mouse Phc2 (54383), Rat Phc2 (313038), domestic cat PHC2 (101082329), dog PHC2 (487297), chicken PHC2 (100857390), cow PHC2 (537511), naked mole-rat Phc2 (101700417), domestic guinea pig Phc2 (100732113), sheep PHC2 (101109942)
UniProtKB ID:
Q8IXK0, A1L4Q1, D3DPR2, Q2TAL3, Q5T0C1, Q6NUJ6, Q6ZQR1, Q8N306
Gene ID:
  • Human(1912) Summary: In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(54383) polyhomeotic-like 2 (Drosophila)
  • Rat(313038) polyhomeotic homolog 2 (Drosophila)
  • domestic cat(101082329) polyhomeotic homolog 2 (Drosophila)
  • dog(487297) polyhomeotic homolog 2 (Drosophila)
  • chicken(100857390) polyhomeotic homolog 2 (Drosophila)
  • cow(537511) polyhomeotic homolog 2 (Drosophila)
  • naked mole-rat(101700417) polyhomeotic homolog 2 (Drosophila)
  • domestic guinea pig(100732113) polyhomeotic homolog 2 (Drosophila)
  • sheep(101109942) polyhomeotic homolog 2 (Drosophila)
  • Horse(100070002) polyhomeotic homolog 2 (Drosophila)

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