PDCD6
programmed cell death 6
Synonyms:
ALG-2, PEF1B
Species:
Human PDCD6 (10016), Mouse Pdcd6 (18570), Rat Pdcd6 (308061), domestic guinea pig Pdcd6 (100716410), naked mole-rat Pdcd6 (101698591), dog PDCD6 (609549), domestic cat PDCD6 (101096541), cow PDCD6 (100125927), sheep PDCD6 (101109042), Zebrafish pdcd6 (393925)
UniProtKB ID:
Gene ID:
- Human(10016) Summary: This gene encodes a calcium-binding protein belonging to the penta-EF-hand protein family. Calcium binding is important for homodimerization and for conformational changes required for binding to other protein partners. This gene product participates in T cell receptor-, Fas-, and glucocorticoid-induced programmed cell death. In mice deficient for this gene product, however, apoptosis was not blocked suggesting this gene product is functionally redundant. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is also located on the short arm of chromosome 5. [provided by RefSeq, May 2012]
- Mouse(18570) programmed cell death 6
- Rat(308061) programmed cell death 6
- domestic guinea pig(100716410) programmed cell death 6
- naked mole-rat(101698591) programmed cell death 6
- dog(609549) programmed cell death 6
- domestic cat(101096541) programmed cell death 6
- cow(100125927) programmed cell death 6
- sheep(101109042) programmed cell death 6
- Zebrafish(393925) programmed cell death 6
- chicken(420988) programmed cell death 6
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