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PCDHGA2

protocadherin gamma subfamily A, 2

Synonyms:
PCDH-GAMMA-A2
Species:
UniProtKB ID:
Gene ID:
  • Human(56113) Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  • Mouse(93710) protocadherin gamma subfamily A, 2
  • Rat(498846) protocadherin gamma subfamily A, 2
  • chicken(431363) protocadherin gamma subfamily A, 2
  • sheep(101104993) protocadherin gamma subfamily A, 2
  • domestic cat(101097204) protocadherin gamma subfamily A, 2
  • cow(539654) protocadherin gamma subfamily A, 2
  • dog(607521) protocadherin gamma subfamily A, 2
  • naked mole-rat(101707494) protocadherin gamma subfamily A, 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-PCDHGA2 antibody produced in mouse, clone 2A7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
mouse
Application
ELISA
western blot
Monoclonal Anti-PCDHGA2 antibody produced in mouse, clone 2A7, ascites fluid,
Species Reactivity
human, mouse
Application
ELISA
western blot
Anti-PCDHGA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-PCDHGA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot