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PCDHGA10

protocadherin gamma subfamily A, 10

Synonyms:
PCDH-GAMMA-A10
Species:
UniProtKB ID:
Gene ID:
  • Human(56106) Summary: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008]
  • Mouse(93722) protocadherin gamma subfamily A, 10
  • Rat(498849) protocadherin gamma subfamily A, 10
  • Horse(100072224) protocadherin gamma subfamily A, 10
  • cow(539554) protocadherin gamma subfamily A, 10
  • sheep(101104577) protocadherin gamma subfamily A, 10
  • dog(487184) protocadherin gamma subfamily A, 10
  • domestic guinea pig(100722477) protocadherin gamma subfamily A, 10
  • domestic cat(101100180) protocadherin gamma subfamily A, 10

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PCDHGA10 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Monoclonal Anti-PCDHGA10 antibody produced in mouse, clone 3A7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot