PCDHA4
protocadherin alpha 4
Synonyms:
CNR1, CNRN1, CRNR1, PCDH-ALPHA4
Species:
Human PCDHA4 (56144), Mouse Pcdha4 (12936), Rat Pcdha4 (116741), cow PCDHA4 (616099), dog PCDHA4 (607212), dog PCDHA4 (607199), chicken PCDHA4 (497214), domestic cat PCDHA4 (101092733), domestic guinea pig Pcdha4 (100713594)
UniProtKB ID:
Gene ID:
- Human(56144) Summary: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
- Mouse(12936) protocadherin alpha 4
- Rat(116741) protocadherin alpha 4
- cow(616099) protocadherin alpha 4
- dog(607212) protocadherin alpha 4
- dog(607199) protocadherin alpha 4
- chicken(497214) protocadherin alpha 4
- domestic cat(101092733) protocadherin alpha 4
- domestic guinea pig(100713594) protocadherin alpha 4
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PCDHA4 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-PCDHA4 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-PCDHA4 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
esiRNA
Product Number
Description
Species