OTX2
orthodenticle homeobox 2
Synonyms:
CPHD6, MCOPS5
Species:
Human OTX2 (5015), Mouse Otx2 (18424), Rat Otx2 (305858), domestic guinea pig Otx2 (100729098), domestic cat OTX2 (101094107), naked mole-rat Otx2 (101696878), sheep OTX2 (101114527), chicken OTX2 (395191), cow OTX2 (538953), Domestic Rabbit OTX2 (100009374) ...More
UniProtKB ID:
Gene ID:
- Human(5015) Summary: This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine. [provided by RefSeq, Jul 2012]
- Mouse(18424) orthodenticle homolog 2 (Drosophila)
- Rat(305858) orthodenticle homeobox 2
- domestic guinea pig(100729098) orthodenticle homeobox 2
- domestic cat(101094107) orthodenticle homeobox 2
- naked mole-rat(101696878) orthodenticle homeobox 2
- sheep(101114527) orthodenticle homeobox 2
- chicken(395191) orthodenticle homeobox 2
- cow(538953) orthodenticle homeobox 2
- Domestic Rabbit(100009374) orthodenticle homeobox 2
- Zebrafish(30501) orthodenticle homolog 2
- dog(490708) orthodenticle homeobox 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-OTX2 Antibody, clone 1O4 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
xenopus, bovine, horse, human, monkey, porcine, rat
Application
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Monoclonal Anti-OTX2 antibody produced in mouse, clone 1H12C4B5, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
flow cytometry
immunofluorescence
immunohistochemistry
western blot
Anti-OTX2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-OTX2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
immunohistochemistry
western blot
western blot
Anti-OTX2 Antibody, clone 6I3J0, Rabbit Monoclonal, ,
Species Reactivity
human, rat
Application
western blot