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NNT

nicotinamide nucleotide transhydrogenase

Synonyms:
GCCD4
Species:
UniProtKB ID:
Gene ID:
  • Human(23530) Summary: This gene encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(18115) nicotinamide nucleotide transhydrogenase
  • Rat(310378) nicotinamide nucleotide transhydrogenase
  • cow(280878) nicotinamide nucleotide transhydrogenase
  • sheep(101121801) nicotinamide nucleotide transhydrogenase
  • dog(479342) nicotinamide nucleotide transhydrogenase
  • domestic cat(101090743) nicotinamide nucleotide transhydrogenase
  • naked mole-rat(101707944) nicotinamide nucleotide transhydrogenase
  • domestic guinea pig(100730359) nicotinamide nucleotide transhydrogenase
  • chicken(427196) nicotinamide nucleotide transhydrogenase
  • Zebrafish(406619) nicotinamide nucleotide transhydrogenase

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-NNT antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Anti-NNT antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
Anti-NNT antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human NNT,
Species
human
MISSION® esiRNA, targeting mouse Nnt,
Species
mouse