NELFA
negative elongation factor complex member A
Synonyms:
NELF-A, WHSC2
Species:
Human NELFA (7469), Mouse Nelfa (24116), Rat Nelfa (305455), domestic guinea pig Nelfa (100733233), naked mole-rat Nelfa (101708884), Zebrafish nelfa (559677)
UniProtKB ID:
Gene ID:
- Human(7469) Summary: This gene is expressed ubiquitously with higher levels in fetal than in adult tissues. It encodes a protein sharing 93% sequence identity with the mouse protein. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene is mapped to the 165 kb WHS critical region, and may play a role in the phenotype of the WHS or Pitt-Rogers-Danks syndrome. The encoded protein is found to be capable of reacting with HLA-A2-restricted and tumor-specific cytotoxic T lymphocytes, suggesting a target for use in specific immunotherapy for a large number of cancer patients. This protein has also been shown to be a member of the NELF (negative elongation factor) protein complex that participates in the regulation of RNA polymerase II transcription elongation. [provided by RefSeq, Jul 2008]
- Mouse(24116) negative elongation factor complex member A, Whsc2
- Rat(305455) negative elongation factor complex member A
- domestic guinea pig(100733233) negative elongation factor complex member A
- naked mole-rat(101708884) negative elongation factor complex member A
- Zebrafish(559677) negative elongation factor complex member A
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-NELFA, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-NELFA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-NELFA antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry
esiRNA
Product Number
Description
Species