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Merck

NDUFA2

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa

Synonyms:
B8, CD14, CIB8
Species:
Human NDUFA2 (4695), Mouse Ndufa2 (17991), Rat Ndufa2 (291660), naked mole-rat Ndufa2 (101709230), domestic guinea pig Ndufa2 (100725776), domestic cat NDUFA2 (101096376), cow NDUFA2 (327698), sheep NDUFA2 (101119470), Zebrafish ndufa2 (554125), chicken NDUFA2 (768860)
UniProtKB ID:
O43678, D6RJD6, Q6IAY8
Gene ID:
  • Human(4695) Summary: The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
  • Mouse(17991) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
  • Rat(291660) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
  • naked mole-rat(101709230) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
  • domestic guinea pig(100725776) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
  • domestic cat(101096376) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
  • cow(327698) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
  • sheep(101119470) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
  • Zebrafish(554125) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
  • chicken(768860) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa
  • dog(478032) NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa

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Antibodies

Product Number
Description
Species Reactivity
Application
WH0004695M1
Monoclonal Anti-NDUFA2 antibody produced in mouse, clone 6E7, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
HPA035933
Anti-NDUFA2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
D150959
1,1-Dimethylbiguanide hydrochloride, 97%,
Species
human
PHR1084
Metformin hydrochloride, Pharmaceutical Secondary Standard; Certified Reference Material,
Species
human
1396309
Metformin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
BP227
Metformin hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human
M-072
Metformin hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human

esiRNA

Product Number
Description
Species
EMU006531
MISSION® esiRNA, targeting mouse Ndufa2,
Species
mouse
EHU027291
MISSION® esiRNA, targeting human NDUFA2,
Species
human