NDE1
nudE neurodevelopment protein 1
Synonyms:
HOM-TES-87, LIS4, NDE, NUDE, NUDE1
Species:
Human NDE1 (54820), Mouse Nde1 (67203), Rat Nde1 (83836), domestic guinea pig Nde1 (100714890), dog NDE1 (100684378), domestic cat NDE1 (101098423), sheep NDE1 (101114156), naked mole-rat Nde1 (101720925), cow NDE1 (508088), Zebrafish nde1 (566146)
UniProtKB ID:
Gene ID:
- Human(54820) Summary: This gene encodes a member of the nuclear distribution E (NudE) family of proteins. The encoded protein is localized at the centrosome and interacts with other centrosome components as part of a multiprotein complex that regulates dynein function. This protein plays an essential role in microtubule organization, mitosis and neuronal migration. Mutations in this gene cause lissencephaly 4, a disorder characterized by lissencephaly, severe brain atrophy, microcephaly, and severe mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]
- Mouse(67203) nuclear distribution gene E homolog 1 (A nidulans)
- Rat(83836) nudE neurodevelopment protein 1
- domestic guinea pig(100714890) nudE nuclear distribution E homolog 1 (A. nidulans)
- dog(100684378) nudE nuclear distribution E homolog 1 (A. nidulans)
- domestic cat(101098423) nudE nuclear distribution E homolog 1 (A. nidulans)
- sheep(101114156) nudE nuclear distribution E homolog 1 (A. nidulans)
- naked mole-rat(101720925) nudE nuclear distribution E homolog 1 (A. nidulans)
- cow(508088) nudE nuclear distribution gene E homolog 1 (A. nidulans)
- Zebrafish(566146) nudE nuclear distribution gene E homolog 1 (A. nidulans)
- chicken(416597) nudE nuclear distribution E homolog 1 (A. nidulans)
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