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MTIF2

mitochondrial translational initiation factor 2

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(4528) Summary: During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(76784) mitochondrial translational initiation factor 2
  • Rat(305606) mitochondrial translational initiation factor 2
  • chicken(421213) mitochondrial translational initiation factor 2
  • cow(281923) mitochondrial translational initiation factor 2
  • naked mole-rat(101711400) mitochondrial translational initiation factor 2
  • domestic guinea pig(100722149) mitochondrial translational initiation factor 2
  • sheep(101122509) mitochondrial translational initiation factor 2
  • dog(474600) mitochondrial translational initiation factor 2
  • domestic cat(101093177) mitochondrial translational initiation factor 2
  • Zebrafish(556465) mitochondrial translational initiation factor 2

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-MTIF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-MTIF2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MTIF2,
Species
human