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Merck

MRPL50

mitochondrial ribosomal protein L50

Synonyms:
MRP-L50
Species:
Human MRPL50 (54534), Mouse Mrpl50 (28028), Rat Mrpl50 (362517), naked mole-rat Mrpl50 (101714730), domestic guinea pig Mrpl50 (100716642), chicken MRPL50 (427307), domestic cat MRPL50 (101096362), cow MRPL50 (514753), fruit fly mRpL50 (38796), dog MRPL50 (474785)
UniProtKB ID:
Q8N5N7, Q5T7E0, Q9NX15
Gene ID:
  • Human(54534) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q. [provided by RefSeq, Jul 2008]
  • Mouse(28028) mitochondrial ribosomal protein L50
  • Rat(362517) mitochondrial ribosomal protein L50
  • naked mole-rat(101714730) mitochondrial ribosomal protein L50
  • domestic guinea pig(100716642) mitochondrial ribosomal protein L50
  • chicken(427307) mitochondrial ribosomal protein L50
  • domestic cat(101096362) mitochondrial ribosomal protein L50
  • cow(514753) mitochondrial ribosomal protein L50
  • fruit fly(38796) mitochondrial ribosomal protein L50
  • dog(474785) mitochondrial ribosomal protein L50
  • sheep(101122162) mitochondrial ribosomal protein L50

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA022925
Anti-MRPL50 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
HPA056854
Anti-MRPL50 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence

esiRNA

Product Number
Description
Species
EHU159341
MISSION® esiRNA, targeting human MRPL50,
Species
human